iS Clinical skincare products are a luxury clinical skincare line trusted by dermatologists, plastic surgeons, and high-end medspas. Known for their multifunctional products, they combine botanical ingredients with pharmaceutical-grade actives to address various skin concerns. Whether you're dealing with inflammation, pigmentation, or ageing, iS Clinical skincare products offer solutions that enhance your skin's natural glow.
New to the brand and wondering how it compares with the rest of your shelf? Our Academy guide to iS Clinical and its science-led formulations sets out the signature actives behind the range and which products suit which routines, while the science behind medical-grade skincare explains what professional-strength formulas do differently. Both are worth reading before you decide where to start.
Want the full picture? Read our complete iS Clinical brand guide in the Skintique Academy.
iS Clinical
iS Clinical Extreme Protect SPF 30 | Anti-Ageing Sunscreen | 100g
£80.00Unit price /UnavailableiS Clinical
iS Clinical Hydra Intensive Cooling Masque | Face Mask | 120g
£95.00Unit price /UnavailableiS Clinical
iS Clinical Youth Body Serum | Hydrating Body Mist | 200ml
£28.00Unit price /UnavailableiS Clinical
iS Clinical Brightening Complex | Brightening Treatment | 30g
£151.00Unit price /UnavailableiS Clinical
iS Clinical Pure Radiance Collection | Brightening Skincare Kit
£266.00Unit price /UnavailableiS Clinical
iS Clinical Youth Complex | Anti-Ageing Treatment | 30g
£158.00Unit price /UnavailableiS Clinical
iS Clinical Extreme Protect SPF 40 | Mineral Sunscreen | 100g
£85.00Unit price /UnavailableiS Clinical
iS Clinical Cleansing Complex Polish | Exfoliating Cleanser | 120g
£48.00Unit price /UnavailableiS Clinical
iS Clinical Moisturizing Complex | Hydrating Moisturiser | 50ml
£98.00Unit price /UnavailableiS Clinical
iS Clinical Cream Cleanser | Moisturising Cream Cleanser | 120ml
£48.00Unit price /UnavailableiS Clinical
iS Clinical Pure Clarity Collection | Blemish-Prone Skin Kit
£202.00Unit price /UnavailableiS Clinical
iS Clinical Tri-Active Exfoliating Masque | Face Mask | 120g
£95.00Unit price /UnavailableiS Clinical
iS Clinical Neckperfect Complex | Neck Firming Cream | 50g
£110.00Unit price /UnavailableiS Clinical
iS Clinical GeneXC Serum | Vitamin C Serum | 15ml & 30ml
£169.00Unit price /Unavailable
Frequently asked questions
Which iS Clinical products should I start with?
Which iS Clinical products should I start with?
Start with Cleansing Complex morning and night, add Active Serum at night for smoother, brighter-looking skin, and finish every morning with Eclipse SPF 50+. Once your skin is settled, layer in Reparative Moisture Emulsion and C Eye Serum Advanced+. This four-step base of cleanse, treat, moisturise and protect is the iS Clinical framework every routine builds from.
How do I use Active Serum without irritating my skin?
How do I use Active Serum without irritating my skin?
Active Serum is potent, so apply one pea-sized amount to dry skin at night and expect a brief tingle as the bionic and glycolic acids get to work. Build to nightly use over two weeks, then add a morning application once your skin tolerates it. Always follow with Eclipse SPF 50+ the next day, since the acids leave skin more sun-sensitive.
What makes Pro-Heal Serum Advance+ different from the other serums?
What makes Pro-Heal Serum Advance+ different from the other serums?
For redness-prone or blemish-prone skin, Pro-Heal Serum Advance+ pairs 15% L-ascorbic acid with vitamins A and E plus olive leaf extract, so it brightens while supporting the barrier. Apply it in the morning under sunscreen, or use it after an in-clinic treatment alongside Sheald Recovery Balm to comfort the look of stressed skin.
What should I use after a peel, needling or laser session?
What should I use after a peel, needling or laser session?
Switch to the calming route: Hydra-Cool Serum for its menthol-cool hydration and Sheald Recovery Balm to shield the skin overnight. Hold off on Active Serum and the Active Peel System until any visible sensitivity has passed, then reintroduce them one at a time over a fortnight.
Are your iS Clinical products genuine, and can you help me choose?
Are your iS Clinical products genuine, and can you help me choose?
We are an authorised UK iS Clinical stockist, so every serum, SPF and balm here is genuine and batch-fresh. If you are unsure whether to begin with Active Serum or Pro-Heal Serum Advance+ for your skin, book a free virtual consultation and we will map the full routine for you.
Not sure which product is right for you?
Book a free virtual consultation with one of our skincare experts — we'll recommend the right routine for your skin.
Book Free Consultation

