2-Bromo-2-Nitropropane-1,3-Diol
INCI: 2-BROMO-2-NITROPROPANE-1,3-DIOL
Reviewed by Daisy · Last updated 14 Aug 2026
Also known as: 2-bromo-2-nitropropane-1,3-diol
A synthetic preservative that helps prevent microbial contamination in skincare formulations
Best For Skin Types
All
Usage Frequency
As formulated
What Is 2-Bromo-2-Nitropropane-1,3-Diol?
2-Bromo-2-nitropropane-1,3-diol (commonly known as Bronopol) is a synthetic preservative used in cosmetic and skincare products to prevent bacterial and fungal growth. It is a halogenated organic compound designed to extend shelf life and maintain product safety during storage and use.
As a preservative, its primary role is to inhibit the proliferation of microorganisms that could otherwise compromise product integrity or pose a risk to skin health. It is found in a relatively small proportion of skincare products on the market.
How It Works
2-Bromo-2-nitropropane-1,3-diol works by inhibiting the growth of bacteria and fungi within a product formulation. It does this through chemical mechanisms that disrupt microbial cell function, preventing colonisation that would otherwise degrade the product or introduce harmful organisms to the skin.
The ingredient is typically used at low concentrations, as preservatives require only minimal amounts to be effective. Its role is purely protective of the product itself rather than providing active skincare benefits.
Clinical Evidence & References
Research indicates that 2-bromo-2-nitropropane-1,3-diol is an effective preservative capable of controlling problematic contamination, including challenging organisms such as Pseudomonas aeruginosa. However, the ingredient has been associated with allergic contact dermatitis in some individuals, particularly those with pre-existing dermatitis or heightened skin sensitivity.
Patch testing can be difficult with this preservative as it may cause irritation even at low concentrations, making it challenging to definitively identify true allergic reactions in all cases. For most people, products preserved with this ingredient are well-tolerated, but those with a history of cosmetic allergies may wish to exercise caution.
How to Use
If using a product containing this preservative, apply as directed by the manufacturer. There is no special usage protocol required beyond standard application instructions. If you have a history of contact dermatitis or sensitive skin, consider patch testing on a small area first, particularly if the product will be used on already irritated or damaged skin.
Safety & Precautions
Frequently Asked Questions
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