Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate
INCI: BIS-ETHYLHEXYL HYDROXYDIMETHOXY BENZYLMALONATE
Reviewed by Kate · Last updated 14 Aug 2026
Also known as: Bis-ethylhexyl Hydroxydimethoxy Benzylmalonate
A synthetic antioxidant that helps regulate sebum and calm inflamed skin
Best For Skin Types
Oily, Combination, Acne-prone
Addresses
Effective Concentrations
2%
Usage Frequency
Daily
What Is Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate?
Bis-ethylhexyl hydroxydimethoxy benzylmalonate is a synthetic antioxidant compound designed to protect skin from oxidative stress. It belongs to a class of ingredients engineered to mimic natural antioxidant behaviours whilst offering stability and consistency in formulated products.
In skincare, this ingredient functions as both an antioxidant and skin conditioner. It works to neutralise free radicals—unstable molecules that can damage skin cells—whilst also helping to regulate sebum production and reduce visible inflammation.
Benefits for Your Skin
How It Works
The ingredient operates primarily by neutralising reactive oxygen species (ROS)—free radicals generated by sun exposure, pollution, and natural skin metabolism. By stabilising these unstable molecules, it reduces the oxidative stress that can lead to inflammation, barrier compromise, and visible skin concerns.
Research also indicates the ingredient may influence sebaceous gland activity, helping to reduce sebum excretion. This dual mechanism—antioxidant action combined with sebum regulation—makes it particularly suited to blemish-prone and oily skin types.
Clinical Evidence & References
A randomised, placebo-controlled study on 44 participants with blemished skin found that 2% bis-ethylhexyl hydroxydimethoxy benzylmalonate produced significant reductions in sebum excretion over 8 weeks. The same study documented measurable improvements in inflamed and red lesions, supported by photographic documentation and expert assessment.
Whilst the antioxidant potential of this ingredient has been demonstrated in laboratory settings, evidence in living skin remains limited to a small number of studies. Further research would help clarify its long-term benefits and optimal concentrations for different skin concerns.
Published Research
How to Use
This ingredient is typically incorporated into serums, moisturisers, and targeted treatments at concentrations around 2%. It integrates well into most skincare routines and does not require special application instructions. For best results, allow 4-8 weeks of consistent use before assessing efficacy, particularly if addressing oiliness or blemish-prone concerns.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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