Camellia Sinensis Callus
INCI: CAMELLIA SINENSIS CALLUS
Reviewed by Daisy · Last updated 2 Jun 2026
Also known as: Camellia Sinensis Callus
Plant cell extract with antioxidant and skin-conditioning properties
Best For Skin Types
All, Oily, Combination, Acne-prone
Addresses
Effective Concentrations
2.5–5%
Usage Frequency
Daily
What Is Camellia Sinensis Callus?
Camellia sinensis callus is a plant cell culture derived from the tea plant (Camellia sinensis). Rather than using the whole leaf, this ingredient uses undifferentiated plant cells grown in a laboratory setting, which can be harvested and processed into an extract. It contains polyphenols and other bioactive compounds naturally present in green tea.
In skincare formulations, it functions primarily as an antioxidant and skin conditioner, helping to protect the skin from oxidative stress and maintain hydration. It also has antimicrobial properties that may support skin health.
Benefits for Your Skin
How It Works
The ingredient works through its polyphenol content, which neutralises free radicals that can damage skin cells and accelerate ageing. This antioxidant action helps protect the skin barrier and reduces oxidative stress.
Research also indicates it may interfere with bacterial quorum sensing—a communication mechanism that allows acne-causing bacteria to coordinate inflammation and biofilm formation. By disrupting this signalling, the extract may help reduce both bacterial virulence and the inflammatory response triggered by these microorganisms.
Clinical Evidence & References
In vitro studies show that Camellia sinensis callus extract can reduce inflammatory markers (IL-6, IL-8, TNF-α) in keratinocytes exposed to acne-causing bacteria, and may inhibit biofilm formation at concentrations of 2.5–5 percent. These results are promising but come from laboratory studies rather than human clinical trials.
While the antioxidant profile of tea plant extracts is well-established, evidence specific to callus-derived material in real-world skincare use remains limited. Further human studies would help clarify its efficacy in routine skincare routines.
How to Use
This ingredient is typically found in serums, toners, essences and moisturisers. As with most plant extracts, consistency matters more than occasional use. It can be layered with other actives, though combining multiple antioxidants is generally unnecessary—choose one or two key antioxidant ingredients to avoid redundancy and potential irritation in sensitive individuals.
Safety & Precautions
Frequently Asked Questions
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