Antioxidant

Camellia Sinensis Callus

INCI: CAMELLIA SINENSIS CALLUS

Reviewed by Daisy · Last updated 2 Jun 2026

Also known as: Camellia Sinensis Callus

Plant cell extract with antioxidant and skin-conditioning properties

Best For Skin Types

All, Oily, Combination, Acne-prone

Addresses

Acne, Redness, Sensitivity, Hydration

Effective Concentrations

2.5–5%

Usage Frequency

Daily

What Is Camellia Sinensis Callus?

Camellia sinensis callus is a plant cell culture derived from the tea plant (Camellia sinensis). Rather than using the whole leaf, this ingredient uses undifferentiated plant cells grown in a laboratory setting, which can be harvested and processed into an extract. It contains polyphenols and other bioactive compounds naturally present in green tea.

In skincare formulations, it functions primarily as an antioxidant and skin conditioner, helping to protect the skin from oxidative stress and maintain hydration. It also has antimicrobial properties that may support skin health.

Benefits for Your Skin

How It Works

The ingredient works through its polyphenol content, which neutralises free radicals that can damage skin cells and accelerate ageing. This antioxidant action helps protect the skin barrier and reduces oxidative stress.

Research also indicates it may interfere with bacterial quorum sensing—a communication mechanism that allows acne-causing bacteria to coordinate inflammation and biofilm formation. By disrupting this signalling, the extract may help reduce both bacterial virulence and the inflammatory response triggered by these microorganisms.

Clinical Evidence & References

In vitro studies show that Camellia sinensis callus extract can reduce inflammatory markers (IL-6, IL-8, TNF-α) in keratinocytes exposed to acne-causing bacteria, and may inhibit biofilm formation at concentrations of 2.5–5 percent. These results are promising but come from laboratory studies rather than human clinical trials.

While the antioxidant profile of tea plant extracts is well-established, evidence specific to callus-derived material in real-world skincare use remains limited. Further human studies would help clarify its efficacy in routine skincare routines.

How to Use

This ingredient is typically found in serums, toners, essences and moisturisers. As with most plant extracts, consistency matters more than occasional use. It can be layered with other actives, though combining multiple antioxidants is generally unnecessary—choose one or two key antioxidant ingredients to avoid redundancy and potential irritation in sensitive individuals.

Safety & Precautions

Generally well-tolerated. As a plant-derived ingredient, patch testing is advisable for those with known sensitivities to Camellia sinensis or related plants.

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