Caprylyl Glucoside
INCI: CAPRYLYL GLUCOSIDE
Reviewed by Emma · Last updated 14 Aug 2026
A gentle plant-derived surfactant that cleanses without disrupting skin barrier function
Best For Skin Types
All, Sensitive, Dry
Addresses
Usage Frequency
Daily
What Is Caprylyl Glucoside?
Caprylyl glucoside is a surfactant derived from plant-based sources, specifically combining a short-chain fatty acid (caprylic acid) with glucose. It belongs to the alkyl polyglucoside family of cleansing agents, which are considered among the gentler options in skincare formulations.
In skincare products, caprylyl glucoside works as a cleanser and emulsifier. Its primary role is to remove oils, dirt and makeup from the skin's surface by helping water and oil-based substances mix together, allowing them to be rinsed away. Unlike some harsher surfactants, it is designed to perform this function whilst minimising disruption to the skin's protective barrier.
How It Works
Caprylyl glucoside functions as a surfactant, meaning it has a molecular structure with one end attracted to water and the other to oils. This dual affinity allows it to surround oily particles and suspend them in water, facilitating their removal during cleansing.
Unlike more aggressive surfactants, caprylyl glucoside is thought to interact more gently with skin proteins and lipids that make up the stratum corneum (the outer layer of skin). This gentler interaction reduces the risk of irritation and barrier disruption, making it particularly valuable in formulations designed for sensitive or compromised skin.
Clinical Evidence & References
Research indicates that alkyl polyglucosides, including caprylyl glucoside, perform well in formulations designed for sensitive skin delivery. Studies comparing caprylyl glucoside to ethoxylated surfactants suggest it may offer a more biocompatible profile, particularly when formulated into microemulsions for drug delivery. This suggests it has potential as a non-irritant cleansing agent.
However, direct clinical evidence specifically evaluating caprylyl glucoside's effects on skin health and tolerance in consumer skincare products remains limited. The existing research focuses primarily on its use as a formulation vehicle rather than a standalone active ingredient. Further human studies would help clarify its long-term safety profile and efficacy in routine skincare use.
Published Research
How to Use
Caprylyl glucoside is typically found in cleansers and micellar waters as part of a blend of surfactants rather than as a sole cleansing agent. It works effectively in both water-based and oil-based formulations. Use as directed on the product label—usually once or twice daily during your cleansing routine. It can be rinsed away with water or used in leave-on formulations depending on the product type.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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