Cetearamidoethyl Diethonium Hydrolyzed Rice Protein

INCI: CETEARAMIDOETHYL DIETHONIUM HYDROLYZED RICE PROTEIN

Reviewed by Emma · Last updated 6 May 2026

A protein derivative from rice that conditions and supports skin barrier function

Best For Skin Types

All, Dry, Sensitive

Addresses

Dryness, Hydration, Barrier repair

Usage Frequency

Daily

What Is Cetearamidoethyl Diethonium Hydrolyzed Rice Protein?

Cetearamidoethyl Diethonium Hydrolyzed Rice Protein is a conditioning agent derived from rice protein that has been chemically modified to improve its stability and performance in skincare formulations. It combines hydrolyzed rice protein—a broken-down form of rice's natural proteins—with fatty acid derivatives to create an ingredient that can penetrate and condition the skin.

This ingredient functions primarily as a skin-conditioning agent, helping to improve the texture and feel of products whilst supporting the skin's natural barrier. It is commonly found across a range of skincare formulations where moisture retention and skin conditioning are desired outcomes.

How It Works

Hydrolyzed rice proteins are amino acid chains small enough to interact with the skin's outer layers. When combined with fatty acid derivatives, this ingredient can deposit onto the skin surface, forming a light occlusive layer that helps trap moisture and prevent water loss. This conditioning effect improves skin feel and appearance without a heavy residue.

The protein component may also interact with the skin's natural lipids and keratin, enhancing the overall conditioning and protective properties of the formulation.

Clinical Evidence & References

Rice-derived ingredients, including hydrolyzed rice proteins, have been evaluated for safety in cosmetics and shown to be well-tolerated across diverse product types. Research indicates that hydrolyzed rice proteins can support skin conditioning and barrier function, though specific clinical studies on this particular derivative are limited.

Most evidence for this ingredient comes from formulatory data and safety assessments rather than dedicated clinical trials. It appears to work synergistically with other conditioning agents to enhance moisturisation, but individual efficacy data for this specific compound remains sparse.

How to Use

This ingredient is typically incorporated into creams, serums, and leave-on treatments where its conditioning properties can be fully utilised. As with most conditioning agents, it works best when used consistently as part of your routine. It should integrate well into most skincare regimens without requiring special application techniques.

Safety & Precautions

Generally well-tolerated based on safety assessments of rice-derived ingredients. Those with known sensitivities to rice or protein-derived ingredients should exercise caution.

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