Colouring Agent/Pigment

CI 45380

Reviewed by Kate · Last updated 14 Aug 2026

A synthetic red colourant used to add colour to skincare formulations

Best For Skin Types

All

Usage Frequency

As directed by product instructions

What Is CI 45380?

CI 45380, also known as Acid Red 87, is a synthetic azo dye used primarily as a cosmetic colorant. It belongs to a class of colour additives approved for use in cosmetic formulations and is employed to impart red or pink hues to skincare products. The ingredient is not naturally derived but is synthesised through chemical processes.

In skincare products, CI 45380 serves purely an aesthetic function—it has no direct active benefit to the skin itself. Its role is to provide visual appeal and consistency in product appearance, helping formulations maintain their intended colour throughout their shelf life.

How It Works

CI 45380 works as a colourant by absorbing and reflecting light at wavelengths that appear red or pink to the human eye. Once incorporated into a skincare formula, it disperses throughout the product to provide even colour distribution. The ingredient itself does not interact with skin biology; it remains on or in the product rather than providing therapeutic effects.

Clinical Evidence & References

Research has examined the stability and retention of CI 45380 in various formulation systems, particularly in relation to its photostability when exposed to sunlight. Studies using lipid-based delivery systems suggest that the colorant's stability can be enhanced through encapsulation techniques, reducing photodegradation under UV exposure.

However, evidence regarding any direct skin benefit or safety concerns specific to CI 45380 in topical skincare remains limited. As with all approved cosmetic colorants, it undergoes regulatory safety assessment, but its function is cosmetic rather than therapeutic.

How to Use

CI 45380 is used at very low concentrations in skincare formulations—typically well below 1% by weight. Because it is a cosmetic additive rather than an active ingredient, there are no specific usage guidelines for consumers. Simply use the product as directed by the manufacturer.

Safety & Precautions

CI 45380 is approved for cosmetic use in most major regulatory jurisdictions. It is generally well-tolerated in topical formulations. As with any cosmetic ingredient, discontinue use if irritation occurs.

Frequently Asked Questions

From the Clinic

Not sure what your skin actually needs?

Two minutes, a few questions, and we’ll point you at what matters — no guesswork.

Take the skin quiz

Learn More About Skincare Ingredients

Explore our comprehensive ingredient glossary to understand what's in your products.

Browse All Ingredients

Authorised Stockist

Official UK retailer

Tracked Delivery

Free UK shipping over £50

5 Star Rating

Trusted by thousands

Expert Advice

Free consultations