Cocamidopropylamine Oxide
INCI: COCAMIDOPROPYLAMINE OXIDE
Reviewed by Daisy · Last updated 14 Aug 2026
Also known as: Cocamidopropylamine Oxide
A coconut-derived surfactant that cleanses and conditions in hair and body formulations
Best For Skin Types
All
Addresses
Effective Concentrations
0.07–4.0%
Usage Frequency
Daily
Cocamidopropylamine Oxide products at Skintique
View all →What Is Cocamidopropylamine Oxide?
Cocamidopropylamine oxide is a surfactant derived from coconut oil. It belongs to a class of molecules called tertiary amine oxides, which are engineered to have both water-loving and oil-loving properties. This dual nature makes it effective at breaking down oils and dirt.
In cosmetic formulations, it functions primarily as a cleansing agent and foam booster in hair and body products. It also has mild conditioning properties, helping to improve the feel and manageability of hair. It appears in roughly 0.1% of skincare products, though it is more common in cleansing and haircare ranges.
How It Works
As a surfactant, cocamidopropylamine oxide works by surrounding oil and dirt molecules, allowing them to be rinsed away with water. Its molecular structure has one end that attracts oil and another that attracts water, making it a natural bridge between the two.
In hair formulations, it also deposits a light conditioning film onto the hair shaft, which can improve shine and reduce friction between strands. This is why it is often found alongside other cleansing agents in shampoos and body washes.
Clinical Evidence & References
Safety assessments by regulatory bodies have evaluated cocamidopropylamine oxide across multiple toxicity studies. The ingredient has shown a favourable safety profile at the concentrations used in cosmetic products (typically 0.07–4.0%), with low acute toxicity in animal models.
The evidence for its cleansing and conditioning efficacy is based on its established chemistry and decades of use in cosmetic formulations rather than extensive published clinical trials. For specific performance claims in individual products, manufacturers rely on in-house testing and formulation data.
Published Research
How to Use
This ingredient is typically used in rinse-off formulations such as shampoos, body washes and cleansing bars, rather than leave-on products. Use as directed on the product label. If used in a cleanser, apply to damp skin or hair, lather gently, and rinse thoroughly with water.
Safety & Precautions
Frequently Asked Questions
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Cocamidopropyl Betainamide Mea Chloride
A coconut-derived surfactant that cleanses and stabilises foam in formulations
Cocamidopropyl Betaine
Gentle cleansing ingredient used in face and body washes | Can be naturally derived or synthetic
Cocamidopropyl Hydroxysultaine
Mild cleansing agent derived from coconut oil | Boosts lather and helps thicken skin care formulas
Coco Betaine
Surfactant derived from coconut oil
Coco-Glucoside
Mixture of a fatty alcohol from coconut oil and the sugar glucose
Coco-Glucoside and Decyl Glucoside
Gentle plant-derived cleansing agents
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