Cocodimonium Hydroxypropyl Silk Amino Acids
INCI: COCODIMONIUM HYDROXYPROPYL SILK AMINO ACIDS
Reviewed by Emma · Last updated 2 Jun 2026
A silk-derived conditioning agent that smooths and protects the skin barrier
Best For Skin Types
All, Dry, Combination, Mature
Addresses
Usage Frequency
Daily
What Is Cocodimonium Hydroxypropyl Silk Amino Acids?
Cocodimonium hydroxypropyl silk amino acids is a conditioning ingredient derived from silk protein that has been chemically modified to be water-soluble. It combines coconut-derived components with silk amino acids to create a positively charged molecule that adheres to the skin and hair.
In skincare formulations, it functions as a skin conditioner and antistatic agent, helping to improve the feel and appearance of the skin's surface by creating a smooth, protective layer.
How It Works
The ingredient works by depositing a thin, positively charged film onto the skin's surface. This film is attracted to the naturally negatively charged outer layers of skin, creating an occlusive layer that helps trap moisture and smooth the texture of the stratum corneum.
Because it is derived from amino acids, it may also have mild film-forming properties that improve the overall feel and appearance of formulations without leaving a greasy residue.
Clinical Evidence & References
Specific clinical studies on this ingredient in skincare are limited. However, silk amino acids and coconut-derived conditioning agents have a long history of use in cosmetic formulations, and both components are generally recognised as safe and effective conditioning agents.
The antistatic and conditioning properties are well-established in the broader cosmetic literature, though targeted research on skin barrier function with this particular derivative would strengthen the evidence base.
How to Use
This ingredient is typically found in rinse-off or leave-on formulations at low to moderate concentrations. It works well in serums, moisturisers, and lightweight lotions. Because it is a conditioning agent rather than an active treatment, it can be used daily as part of a broader skincare routine without concern for tolerance issues in most skin types.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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