Dextran Sulfate
INCI: DEXTRAN SULFATE
Reviewed by Emma · Last updated 14 Aug 2026
Also known as: Dextran Sulfate
A polysaccharide that conditions and binds moisture to the skin surface
Best For Skin Types
All, Dry, Sensitive
Addresses
Usage Frequency
Daily
What Is Dextran Sulfate?
Dextran sulfate is a synthetic polysaccharide derived from dextran, a complex carbohydrate. In skincare formulations, it functions as both a binder and skin conditioning agent, helping to improve the texture and feel of products whilst supporting the skin's hydration.
The ingredient works by creating a protective film on the skin surface, which can help retain moisture and improve the overall sensory experience of a formula.
How It Works
Dextran sulfate is a humectant-like ingredient that attracts and holds water molecules at the skin surface. Its molecular structure allows it to form a thin, occlusive film that helps prevent moisture evaporation whilst also improving how products feel when applied.
The ingredient's binding properties also allow it to stabilise formulations and enhance their consistency, which indirectly benefits skin by ensuring even product distribution.
Clinical Evidence & References
Research into dextran sulfate has primarily focused on its use in drug delivery systems and internal inflammation models rather than topical skincare applications. Evidence specific to its cosmetic use in skincare is limited.
The ingredient is established as a safe, well-tolerated humectant in cosmetic formulations, but robust clinical trials examining its direct benefits for skin conditions are sparse. It functions effectively as a conditioning agent based on its chemical properties and established safety profile.
Published Research
How to Use
Dextran sulfate is typically used in creams, serums, and hydrating formulations where its film-forming and moisture-binding properties can be most effective. It works well alongside other hydrating ingredients and does not require special application techniques. Use as directed within your chosen product.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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