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Diethyl Ethanolamine

INCI: DIETHYL ETHANOLAMINE

Reviewed by Rosie · Last updated 14 Aug 2026

A pH buffer that helps stabilise skincare formulations and maintain skin compatibility

Best For Skin Types

All

Addresses

Sensitivity, Irritation

Usage Frequency

Daily

What Is Diethyl Ethanolamine?

Diethyl ethanolamine is a small organic compound that acts as a buffering agent in skincare products. Its primary role is chemical rather than active: it helps maintain the pH of formulations within ranges that are gentle on skin and safe for use.

When added to skincare products, it works to neutralise excess acidity or alkalinity, ensuring the final formula sits at a pH level compatible with the skin's natural acid mantle. This is particularly important in products containing active ingredients that might otherwise be too harsh or unstable at their natural pH.

How It Works

Diethyl ethanolamine functions as a pH buffer by accepting or donating hydrogen ions as needed. When a formulation becomes too acidic, the buffer accepts excess hydrogen ions; when it becomes too alkaline, it donates them. This equilibrium keeps the product's pH stable over time and through storage.

The skin's natural pH is slightly acidic (around 4.5–5.5). Products formulated at this pH are less likely to disrupt the acid mantle—the protective layer that maintains skin barrier function and defends against irritation and pathogenic bacteria.

Clinical Evidence & References

Limited direct clinical evidence exists specifically for diethyl ethanolamine as a skincare ingredient in isolation. However, the principle of pH buffering in skincare is well-established: maintaining formulations at skin-compatible pH levels minimises irritation and supports barrier function. Research consistently shows that products formulated at excessively high or low pH can compromise skin health and increase transepidermal water loss.

Diethyl ethanolamine has been used in cosmetics for decades and is generally considered safe at permitted concentrations. As with many functional ingredients, its benefit lies in enabling other active ingredients to work safely and effectively rather than delivering direct skin benefits itself.

How to Use

No specific usage guidance is needed for products containing diethyl ethanolamine—it is a functional ingredient that works behind the scenes. Simply use the product as directed. If you are using multiple active ingredients (vitamin C, niacinamide, acids, etc.), ensure the formulation is pH-balanced; a well-buffered product will feel more comfortable on skin and allow actives to perform optimally without excessive irritation.

Safety & Precautions

Diethyl ethanolamine is considered safe in cosmetic formulations at permitted levels. It is well-tolerated by most skin types and is unlikely to cause irritation when used as a buffer agent.

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