Diosmine
INCI: Diosmin
Reviewed by Daisy · Last updated 18 Aug 2026
Also known as: Diosmin
Citrus-derived flavonoid Potent antioxidant
EWG Safety Score
What Is Diosmine?
Diosmine is a flavonoid found in citrus fruits. It has been used for years as a supplement and medical treatment for vascular conditions; however, it’s now gaining popularity as an anti-ageing skin care ingredient.
Due to its flavonoid nature, diosmine is a potent antioxidant, with abilities to help stave off premature signs of ageing, including fine lines and wrinkles.
Studies also demonstrate that disomine has a soothing effect on skin and can help inhibit the development of elastase and collagenase, two enzymes which break down elastin and collagen, meaning it is a valuable ingredient for use in products designed to maintain skin firmness.
Note: There are two spellings for this ingredient. “Diosmine” is used for cosmetics while “Diosmin” is the technical name referred to in scientific literature.
Benefits for Your Skin
Clinical Evidence & References
- Journal of Clinical and Aesthetic Dermatology, January 2024, pages 15-23
- Molecules, November 2022, pages 1-10 and July 2022, pages 1-12
- European Journal of Drug Metabolism and Pharmokinetics, October 2021, pages 1-18
- Phytomedicine, January 2021, ePublication
- Journal of Cosmetic Dermatology, October 2018, pages 848-856
From the Clinic
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