Disodium EDTA
Reviewed by Rosie · Last updated 18 Aug 2026
Also known as: Tetrasodium EDTA, Trisodium EDTA, EDTA
One of the salt forms of ethylenediaminetetraacetic acid | Helps enhance the stability of cosmetics formulas
Addresses
EWG Safety Score
What Is Disodium EDTA?
Disodium EDTA is a salt of ethylenediaminetetraacetic acid (commonly known as EDTA). In cosmetics, it functions primarily as a chelating agent, meaning it prevents ingredients in a formula from binding with trace elements (mainly minerals) that can be present in water or other ingredients. This action enhances the stability of cosmetics formulas and helps makes the job of preservatives easier since EDTA ingredients bond with mineral ions that microorganisms need to remain intact. In addition to being used in makeup, skin care, and hair care products, disodium EDTA is also used as a food additive.
In several studies, the Cosmetics Review Board has found that as used in cosmetics products, disodium EDTA is safe. It was determined that in the concentrations used in commercial cosmetics, it is not a skin sensitizer nor a carcinogen, and does not penetrate through skin. The highest concentration of disodium EDTA used in leave-on products is 0.85% (for hair color sprays).
Clinical Evidence & References
Published Research
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Cosmeticsinfo.org, Accessed November 2021, ePublication []
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Cosmetic Ingredient Review, June 2019, pages 1-77 []
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European Commission Directorate General for Health and Consumers, September 2015, ePublication []
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