Prebiotic/Probiotic/Postbiotic

Epidermidibacterium Keratini Ferment Filtrate

INCI: EPIDERMIDIBACTERIUM KERATINI FERMENT FILTRATE

Reviewed by Emma · Last updated 2 Jun 2026

A postbiotic ferment that supports skin barrier function and elasticity

Best For Skin Types

All, Sensitive, Dry

Addresses

Barrier repair, Dryness, Hydration, Sensitivity

Usage Frequency

Daily

What Is Epidermidibacterium Keratini Ferment Filtrate?

Epidermidibacterium Keratini Ferment Filtrate is a postbiotic ingredient derived from fermented bacterial cultures. Postbiotics are the metabolic byproducts created when beneficial bacteria ferment, and this particular filtrate comes from a strain selected for its effects on skin health. It functions primarily as an emollient and skin conditioner.

Rather than containing live bacteria, this ingredient delivers the beneficial compounds produced during fermentation. These are designed to support the skin's natural functions, particularly around barrier integrity and elasticity.

How It Works

This ferment filtrate appears to work through multiple pathways. As an emollient, it creates a protective layer that helps prevent transepidermal water loss, supporting barrier function. More specifically, the postbiotic metabolites may interact with skin cells and the microbiome to promote structural integrity.

Research suggests it may also influence skin microbiome composition by favouring beneficial commensal bacteria, though the complete mechanism of action requires further investigation.

Clinical Evidence & References

A prospective clinical study in Asian women found that topical application of this ingredient led to measurable improvements in barrier function, skin elasticity, and dermal density compared to placebo. Biophysical measurements were used to assess these changes objectively.

The research also indicated the ingredient was well-tolerated and appeared to support a diverse, balanced skin microbiome. However, evidence remains relatively limited, and further studies across different skin types and populations would strengthen our understanding of its efficacy and range of benefits.

How to Use

This ingredient is typically incorporated into serums, moisturisers, and barrier-support products. It works well as part of a broader skincare routine and does not require special handling. Apply to clean, damp skin as directed by the product formulation, usually once or twice daily depending on your routine.

Safety & Precautions

Generally well-tolerated in clinical settings. As with any new ingredient, patch-test first if you have sensitive skin or are prone to reactions.

Frequently Asked Questions

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