Antioxidant

Genistein

Reviewed by Emma · Last updated 18 Aug 2026

Belongs to a set of compounds known as isoflavones, which are sources of phytoestrogens Commonly derived from soy

What Is Genistein?

Genistein is a naturally occurring plant ingredient that belongs to a group of compounds known as isoflavones. Isoflavones are sources of phytoestrogens, also known as plant estrogens, that are not hormones but can connect with receptor sites on skin’s surface, helping it look and feel younger. Genistein is most often derived from soy but can also be produced synthetically (’s Choice Skincare uses the natural variety).

As an isoflavone, genistein is a rich source of antioxidants that have impressive skin-soothing properties. Research shows that genistein has multiple benefits for skin, both when it’s ingested and used topically. Applied to skin, genistein exhibits anti-ageing effects, including reducing the visible appearance of wrinkles and helping protect skin from the effects of sun damage.

It penetrates skin better than “sister” isoflavone daidzein, but research has shown that these ingredients work even better when paired in a single formula. This is due to the synergy they share as well as both having an affinity for key receptor sites on skin’s surface.

Emerging studies also show genistein has a special ability to improve signs of ageing and dry skin that are common during menopause. It is typically used in amounts of 0.251% for these benefits, although studies have been done looking at concentrations up to 4%.

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Other forms of Genistein

These appear on ingredients lists under different names but are the same substance. Genistein is the common form.

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