Emollient

Glucosyl Hesperidin

INCI: Hesperidin

Reviewed by Emma · Last updated 18 Aug 2026

Also known as: Hesperidin

Synthetic water-soluble form of the flavonoid hesperidin Has antioxidant properties + can improve barrier function

What Is Glucosyl Hesperidin?

Glucosyl hesperidin is a water-soluble form of hesperidin, a flavonoid found in many citrus plants, as well as in evening primrose oil. Whereas hesperidin is natural, glycosyl hesperidin is synthetic. Its water solubility means it is more readily absorbed by the skin.

Research shows hesperidin has antioxidant properties and when applied topically, can help improve skin's barrier function. There are also studies showing it has skin-soothing benefits and that it can improve the appearance of uneven skin tone.

Aside from its skin care use, glucosyl hesperidin is also used as a food additive and has been determined “generally ruled as safe” (GRAS) by the United States Food & Drug Administration.

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