Glycine Max Leaf Extract
INCI: GLYCINE MAX LEAF EXTRACT
Reviewed by Emma · Last updated 2 Jun 2026
Also known as: Glycine Max Leaf Extract
A plant-derived antioxidant that may help calm inflammatory skin conditions
Best For Skin Types
All, Sensitive, Combination
Addresses
Usage Frequency
Daily
What Is Glycine Max Leaf Extract?
Glycine Max Leaf Extract is derived from soybean leaves and contains bioactive compounds including isoflavones, allantoin, and alpha-hydroxy acids. These naturally occurring substances have been used traditionally in skincare and are now incorporated into modern formulations for their antioxidant and skin-conditioning properties.
The extract functions primarily as an antioxidant and skin protectant, helping to defend against environmental stressors whilst supporting the skin's natural barrier function.
Benefits for Your Skin
How It Works
The extract contains isoflavones and other polyphenolic compounds that act as free radical scavengers, reducing oxidative damage to skin cells. Additionally, research indicates it may modulate inflammatory signalling pathways—specifically JAK/STAT signalling—which is involved in conditions characterised by excessive inflammation.
The presence of allantoin and alpha-hydroxy acids contributes to skin conditioning and barrier repair, whilst the overall composition supports the skin's natural defence mechanisms against environmental aggressors.
Clinical Evidence & References
Research on wild soybean leaf and stem extract suggests potential benefits for inflammatory skin conditions. In laboratory and animal models, the extract demonstrated effects on inflammatory markers associated with atopic dermatitis, including reduced expression of inflammatory cytokines and improved skin barrier function measured through reduced transepidermal water loss.
However, most evidence comes from in vitro and animal studies rather than extensive human clinical trials. A cosmetic ingredient safety panel assessed soy-derived ingredients and concluded that soy leaf extract is safe as used in cosmetics, though further human data would strengthen confidence in its efficacy claims. The mechanism appears plausible, but real-world effectiveness in typical formulation concentrations requires more investigation.
Published Research
How to Use
Glycine Max Leaf Extract is typically used as part of a broader formulation rather than as a standalone active. It works well within serums, moisturisers, and soothing treatments. There is no specific timing required, and it can be incorporated into both morning and evening routines. It pairs well with other antioxidants and barrier-supporting ingredients.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Glutathione
Occurs naturally in skin Defends against environmental damage
Glyceryl Ascorbate
Made by binding ascorbic acid with hydrating glycerin Helps visibly fade discolouration by inhibiting transfer of excess melanin
Glyceryl Glucoside
Composed of skin-loving glycerin and glucose A humectant that draws moisture to skin
Glycine Soja (Soybean) Seed Extract
Rich source of antioxidants, including isoflavones proven to help skin Defends skin from environmental aggressors
Glycine Soja Seed Extract
Derived from soybeans Has antioxidant abilities
Glycyrrhetic Acid
One of the active, skin-soothing components of licorice extract
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