Gynostemma Pentaphyllum Callus Extract

Gynostemma pentaphyllum callus extract is derived from cultured plant cells of Gynostemma pentaphyllum, a plant traditionally used in Asian herbal medicine. The extract is rich in bioactive compounds, particularly polydeoxyribonucleotides (PDRN) — small DNA fragments that occur naturally in plant tissue.In skincare formulations, this ingredient functions as an antioxidant and skin conditioner. It may also offer mild antimicrobial properties, though research in cosmetic applications remains limited. As a plant-based source of PDRN, it represents an alternative to animal-derived versions.

The polydeoxyribonucleotides in this extract are thought to interact with adenosine receptors in skin cells, potentially promoting cellular repair and regeneration processes. This mechanism is similar to how animal-derived PDRN functions, though the cosmetic significance of plant-derived versions is still being investigated.As an antioxidant, the extract's bioactive compounds may help protect skin cells from damage caused by environmental stressors such as UV exposure and pollution.

This ingredient is typically found in serums, essences, and moisturisers at low concentrations. It works well alongside other antioxidants and hydrating ingredients. There is no evidence to suggest specific timing or frequency restrictions; use as directed by the product formulation.

Generally well-tolerated in cosmetic products. Those with known sensitivities to plant extracts should patch test first.