Skin Conditioning

Hordeum Vulgare Seed Extract

INCI: HORDEUM VULGARE SEED EXTRACT

Reviewed by Daisy · Last updated 14 Aug 2026

A plant-derived skin conditioning agent derived from barley seeds

Best For Skin Types

All

Addresses

Dryness, Hydration

Usage Frequency

Daily

What Is Hordeum Vulgare Seed Extract?

Hordeum vulgare seed extract is derived from barley seeds, a cereal grain. The extract contains bioactive compounds including lunasin, a peptide that has been identified across barley cultivars and demonstrates bioavailability in biological systems.

In skincare formulations, this ingredient functions as a skin conditioning agent, meaning it is intended to help maintain skin in good condition. It remains relatively uncommon in cosmetic products, appearing in approximately 0.1% of skincare formulations.

How It Works

The skin conditioning effect is primarily achieved through the ingredient's composition of bioactive compounds. Lunasin, a 43-amino acid peptide present in barley, has shown the ability to remain intact and bioactive when absorbed into biological systems, including localising to cell nuclei.

The precise mechanism by which barley seed extract improves skin condition in topical applications requires further research, as most studies examining lunasin have focused on ingestion or cell culture models rather than direct skin application.

Clinical Evidence & References

Research has established that lunasin is present across barley cultivars and remains bioavailable and bioactive in biological systems. Studies in mammalian models and cell cultures have demonstrated activity related to histone acetyl transferases, though the relevance of these mechanisms to topical skincare benefits remains to be clarified.

The safety assessment of barley-derived ingredients, including seed-derived extracts, concluded these ingredients are safe in cosmetics at typical use concentrations and practices. However, the specific efficacy of this ingredient for particular skin concerns in topical products has not been extensively documented in published clinical trials.

How to Use

Barley seed extract is typically incorporated into serums, moisturisers, and treatment products at low concentrations. As with any botanical ingredient, introduce it gradually if you have sensitive skin. It can be used alongside other skincare ingredients, though patch testing is advisable if you have a known cereal grain sensitivity.

Safety & Precautions

Barley seed extract has been assessed as safe for cosmetic use under standard manufacturing practices and concentrations. Those with IgE-mediated wheat allergy should be aware of potential cross-reactivity with barley, though clinical relevance varies by individual.

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Part of a family

Hordeum Vulgare Seed Extract is a variant of Hordeum Vulgare Leaf Extract, the form you will most often see on an ingredients list.

A barley-derived extract with potential skin-conditioning and antioxidant properties

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