Isohexadecane
Reviewed by Emma · Last updated 18 Aug 2026
Also known as: Isododecane
Versatile ingredient used as a cleansing agent, solvent, texture enhancer, and skin-conditioning agent | Imparts a non-greasy, lightweight, silky feel
Addresses
EWG Safety Score
What Is Isohexadecane?
Isohexadecane is a multitalented synthetic ingredient used as a cleansing agent, solvent, texture enhancer, and skin-conditioning agent. Even though it is often used to increase the richness of a formula’s texture, isohexadecane imparts a non-greasy, lightweight, silky feel on skin and is described as having a powder-like finish. Its dry-but-non-drying finish makes it popular in products geared toward oily skin.
The cleansing/solvent properties of isohexadecane also make it a common choice in makeup remover formulas where it helps break down long-wear foundation, mascara, etc. It’s also used in hair care products to add silkiness without weighing hair down.
Isohexadecane has been deemed safe by the Cosmetic Ingredient Review Expert Panel. Their assessment surveyed products containing up to a 42% concentration.
Clinical Evidence & References
Published Research
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MakingCosmetics.com, Accessed October 2021, ePublication [https://www.makingcosmetics.com/ELL-ISOHEX-01.html]
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Colloids and Surface B: Biointerfaces, September 2020, ePublication [https://www.sciencedirect.com/science/article/abs/pii/S0927776520303623]
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International Journal of Cosmetic Science, December 2018, ePublication [https://onlinelibrary.wiley.com/doi/abs/10.1111/ics.12498]
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International Journal of Toxicology, January 2012, pages 2,69S-2,95S [https://journals.sagepub.com/doi/pdf/10.1177/1091581812463087]
Frequently Asked Questions
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