Isoquercitrin

Isoquercitrin is a naturally occurring flavonoid—a type of plant compound with antioxidant properties. It is the glucoside form of quercetin, meaning a glucose molecule is attached to quercetin, which can be found in various plant species including peanut skin and other botanical sources. In skincare, it functions primarily as an antioxidant.Antioxidants work by neutralising free radicals, unstable molecules that can accumulate in skin from environmental stressors such as UV exposure and pollution. By reducing oxidative stress, isoquercitrin may help support skin's natural defence mechanisms.

Isoquercitrin functions as a free radical scavenger, meaning it can donate electrons to unstable free radical molecules and render them harmless. This reduces oxidative stress within skin cells. The ingredient appears to work through several biochemical pathways, including suppression of inflammatory signalling pathways and enhancement of the skin's own antioxidant enzyme systems.In research models, isoquercitrin has demonstrated the ability to upregulate protective enzymes such as superoxide dismutase whilst simultaneously reducing inflammatory cytokines—signalling molecules involved in in…

Isoquercitrin is typically incorporated into serums, moisturisers, and targeted treatment products. It can be used alongside other antioxidants as part of a broader skincare strategy to support skin health and environmental protection. For best results, use consistently as part of your routine and combine with daily sun protection, as topical antioxidants work alongside—not as a replacement for—sunscreen.

Isoquercitrin appears to be well-tolerated with a low irritation and sensitisation hazard. No specific cautions are documented, though as with any ingredient, patch testing is advisable for those with sensitive skin.