Larrea Tridentata Extract
INCI: LARREA TRIDENTATA EXTRACT
Reviewed by Rosie · Last updated 2 Jun 2026
A plant extract with antioxidant properties traditionally used for skin health
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Larrea Tridentata Extract?
Larrea tridentata extract comes from creosote bush, a perennial shrub native to the deserts of northern Mexico and the southwestern United States. The plant has been used in traditional medicine for centuries to address various health concerns, including skin-related issues.
In skincare, larrea tridentata extract functions primarily as a skin conditioning agent. It contains polyphenolic compounds that contribute antioxidant activity, which may help protect skin from environmental stressors.
How It Works
Larrea tridentata extract works primarily through its polyphenolic compounds, which have antioxidant properties. These compounds can help neutralise free radicals—unstable molecules that contribute to premature ageing and skin damage when they accumulate in the skin.
The extract may also support the skin's natural conditioning and hydration mechanisms, though the exact mechanisms in topical skincare are not fully established.
Clinical Evidence & References
Research into larrea tridentata has primarily focused on systemic health applications rather than topical skincare. Laboratory studies suggest the extract possesses antiproliferative and antioxidant activity in melanoma cell models, indicating potential protective mechanisms at a cellular level.
However, human clinical data specifically evaluating this ingredient in skincare formulations is limited. The traditional use in Mexican and Native American medicine for skin concerns is well-documented, but translating this into evidence-based skincare claims requires more robust clinical research.
How to Use
Larrea tridentata extract is typically found in serums, creams and toners at varying concentrations. Use as directed by the specific product formulation. If using in a layered routine, apply after cleansing and toning but before heavier moisturisers, allowing each layer to absorb.
Safety & Precautions
Frequently Asked Questions
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