Lithospermum Erythrorhizon Root
INCI: LITHOSPERMUM ERYTHRORHIZON ROOT
Reviewed by Kate · Last updated 14 Aug 2026
A traditional plant root extract with moisturising and antioxidant properties
Best For Skin Types
All, Dry, Sensitive, Mature
Addresses
Usage Frequency
Daily
What Is Lithospermum Erythrorhizon Root?
Lithospermum erythrorhizon root is derived from gromwell, a plant with a history in traditional medicine. The root contains naphthoquinone pigments, including a compound called shikonin, which give the extract its characteristic deep colour and biological activity.
In skincare formulations, it functions as a skin conditioning agent. The extract works to support skin hydration and help protect against environmental stressors, with research suggesting it may offer both moisturising and antioxidant benefits.
How It Works
The naphthoquinone compounds in lithospermum root, particularly shikonin, work through multiple pathways. They help increase the skin's ability to retain water by supporting the moisture-binding capacity of the stratum corneum (the outermost skin layer). Additionally, these compounds scavenge free radicals and help suppress inflammatory signalling pathways that can be triggered by UV exposure or other stressors.
The extract may also help protect skin cells from glycation—a process where sugar molecules bond to proteins and can compromise skin structure and elasticity over time.
Clinical Evidence & References
Research on cosmetic formulations containing this extract shows moisturising effects when applied twice daily over four weeks, with benefits appearing to be dose-dependent. Studies conducted on cultured human skin cells have demonstrated that the extract and its active compounds can reduce UVB-induced inflammation, suppress inflammatory signalling, and enhance the skin's antioxidant defences.
Evidence also suggests the extract may inhibit glycation and the formation of advanced glycation end products. However, most research to date has been conducted in controlled laboratory settings or short-term human studies, so the long-term benefits in real-world use remain less well characterised. More extensive clinical trials would help clarify efficacy in diverse populations and skin types.
Published Research
How to Use
Lithospermum erythrorhizon is typically incorporated into serums, moisturisers, and emulsions. Since it is usually part of a formulated product rather than a standalone ingredient, follow the application instructions provided by the product manufacturer. For best results, use consistently as directed, typically twice daily. If combining with other actives, introduce gradually to monitor how your skin responds.
Safety & Precautions
Frequently Asked Questions
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Take the skin quizOther forms of Lithospermum Erythrorhizon Root
These appear on ingredients lists under different names but are the same substance. Lithospermum Erythrorhizon Root is the common form.
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