Mahonia Aquifolium Root Extract
Reviewed by Rosie · Last updated 14 Aug 2026
Also known as: Oregon grape, Berberis aquifolium
Skin-calming ingredient, also known as Oregon grape
EWG Safety Score
What Is Mahonia Aquifolium Root Extract?
Mahonia aquifolium root extract, also known as Oregon grape and Berberis aquifolium, functions as a skin-calming ingredient. A great deal of the research behind this ingredient has shed light on its significant antioxidant properties that help protect skin from the ravaging effects of sun damage. Other research relates directly to its use for addressing sensitive skin issues that lead to redness, flaking, and discomfort.
Mahonia is a shrub of the plant family Berberidaceae, including species native to East Asia, North America and Central America.
Cosmetic suppliers of this ingredient describe it is as a slightly viscous brown liquid in raw material form. Usage levels range from 0.1–1%, the higher amount being if it's part of a blend. A formal safety assessment hasn't been conducted; however, studies on compromised human skin have shown it is well tolerated, with only a slight risk of sensitization (and remember, this was on compromised skin).
Clinical Evidence & References
Published Research
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Bio-Botanica Inc., Accessed September 2021, ePublication Bio-Botanica Inc., 2021
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The Journal of Clinical and Aesthetic Dermatology, December 2018, pages 42–47 The Journal of Clinical and Aesthetic Dermatology, 2018
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Molecules, February 2021, pages 1-17 Molecules, 2021
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Journal of Ethnopharmacology, September 2009, pages 297-303 Journal of Ethnopharmacology, 2009
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Fitoterapia, November 2007, pages 802-806 Fitoterapia, 2007
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Journal of Inflammation, July 2007, pages 1-7 Journal of Inflammation, 2007
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American Journal of Therapeutics, September 2005, pages 398-406 American Journal of Therapeutics, 2005
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Bioorganic and Medicinal Chemistry, September 2004, pages 4,709-4,715 Bioorganic and Medicinal Chemistry, 2004
From the Clinic
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Take the skin quizOther forms of Mahonia Aquifolium Root Extract
These appear on ingredients lists under different names but are the same substance. Mahonia Aquifolium Root Extract is the common form.
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