Melia Azadirachta Branch/Leaf Extract

Melia azadirachta, commonly known as neem, is a tree native to the Indian subcontinent. This ingredient is derived from the branch and leaf extract of the plant, which has a long history of use in traditional skincare practices across South Asia.In skincare formulations, neem leaf extract is primarily used for its skin-protecting properties. It contains compounds including fatty acids and polyphenols that help support the skin's natural defences against environmental stressors.

Neem leaf extract works primarily through its polyphenol and fatty acid content. These compounds act as antioxidants, helping to neutralise free radicals generated by UV exposure and pollution. This antioxidant action reduces oxidative stress on skin cells.The extract also contains compounds that interact with skin's natural immune responses, potentially moderating inflammatory pathways and supporting the skin barrier's structural integrity through its lipid profile.

Neem extract is typically found in serums, creams and targeted treatment products at low concentrations. It can be used daily as part of a routine skincare regimen, usually in the morning or evening depending on the formulation. If combining with other active ingredients, introduce gradually to assess tolerance, as neem can have a distinctive sensory profile.

Neem is generally well-tolerated in topical skincare formulations. Some individuals may experience mild irritation or sensitivity, particularly if the skin barrier is compromised; patch testing is advisable for sensitive skin.