Menaquinone-7
INCI: MENAQUINONE-7
Reviewed by Emma · Last updated 14 Aug 2026
A form of vitamin K that may support skin protection and sebum regulation
Best For Skin Types
All, Oily, Combination
Addresses
Usage Frequency
Daily
What Is Menaquinone-7?
Menaquinone-7 (MK-7) is a naturally occurring form of vitamin K, a fat-soluble micronutrient found in fermented foods and produced by certain bacteria. In skincare formulations, it functions as a skin-protecting agent with reported astringent and sebum-regulating properties.
Vitamin K plays a role in various physiological processes, including protein synthesis and cellular signalling. When applied topically, menaquinone-7 is thought to influence skin behaviour through these mechanisms, though the exact pathways in cosmetic use remain an area of ongoing investigation.
How It Works
Menaquinone-7 is believed to work through multiple pathways. As a form of vitamin K, it participates in protein synthesis and cellular signalling processes that may influence sebaceous gland activity and skin barrier function.
The astringent effect is thought to result from the ingredient's interaction with skin proteins, potentially creating a subtle tightening sensation. However, the exact mechanisms of topical menaquinone-7 in cosmetic formulations are not fully characterised, and further research would help clarify its precise mode of action on skin.
Clinical Evidence & References
Evidence for menaquinone-7 in skincare is limited. Most published research examines vitamin K supplementation systemically (oral intake) rather than topical application, and focuses on medical conditions such as bone health and blood coagulation rather than cosmetic skin benefits.
Available data suggests that topical vitamin K may support skin health and potentially address oiliness, but robust clinical trials specifically investigating menaquinone-7 in skincare products are scarce. Claims regarding its efficacy should be approached with appropriate caution until further evidence accumulates.
How to Use
Menaquinone-7 is typically included in serums, moisturisers and targeted treatments. Use according to product instructions, generally applied to clean skin once or twice daily. It can be layered with other skincare ingredients, though as with any new product, introduce it gradually to monitor skin response.
Safety & Precautions
Frequently Asked Questions
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