Best For Skin Types
All, Sensitive, Combination
Addresses
Usage Frequency
Daily
What Is Methylsilanol Glycyrrhizinate?
Methylsilanol Glycyrrhizinate is a hybrid ingredient combining silicone chemistry with glycyrrhiza (liquorice root) extract. It's created by chemically bonding a methyl silanol group to glycyrrhizinate, the active compound found in liquorice. This modification is designed to improve stability and skin penetration compared to standard liquorice extract.
The ingredient functions primarily as a skin conditioning agent, helping to improve how the skin feels and appears on the surface.
How It Works
The silicone component of this ingredient allows it to form a light conditioning film on the skin's surface, which can help lock in moisture and smooth the appearance of the stratum corneum (the outermost skin layer). The glycyrrhizinate component works through the skin's natural inflammatory response pathways, helping to reduce visible redness and irritation.
The combination may offer better stability than liquorice extract alone, potentially allowing the soothing properties to persist longer on the skin.
Clinical Evidence & References
Evidence specific to Methylsilanol Glycyrrhizinate is limited in published dermatological research. Most supporting data comes from ingredient supplier studies rather than independent clinical trials. Liquorice derivatives are well-documented for calming properties, but the addition of the silicone group means this particular compound's profile may differ from standard glycyrrhizinate.
It appears in skincare products marketed for sensitive and reactive skin types, suggesting cosmetic chemists view it as a functional soothing agent, though more rigorous clinical evaluation would help clarify its efficacy.
How to Use
This ingredient is typically found in rinse-off products, serums, creams and masks rather than leave-on treatments. It works well alongside other calming ingredients like centella asiatica or allantoin. There is no evidence of an upper limit for daily use, though as with any skincare ingredient, introduction should be gradual if you have very reactive skin.
Safety & Precautions
Frequently Asked Questions
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Lauryl Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone
A silicone-based conditioning agent that smooths and protects skin and hair
Methicone
One of the simpler silicones due to its less complex molecular structure
Methoxy Amodimethicone/Silsesquioxane Copolymer
A silicone copolymer that forms a protective film on skin and hair
Methylsilanol Hydroxyproline Aspartate
A silicone-based conditioning agent that smooths and protects the skin barrier
Methylsilanol PCA
A silicon-based humectant that draws moisture into the skin and reinforces its barrier function
PEG-10 Dimethicone
A silicone-based conditioning agent that smooths the skin surface and improves texture
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