Mycosporine Glycine
INCI: MYCOSPORINE GLYCINE
Reviewed by Kate · Last updated 14 Aug 2026
Also known as: Mycosporine Glycine
A natural antioxidant derived from algae that protects skin from UV damage and oxidative stress
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Mycosporine Glycine?
Mycosporine glycine is a naturally occurring amino acid compound found in certain algae and cyanobacteria. It belongs to a family of molecules known as mycosporine-like amino acids (MAAs), which these organisms produce to protect themselves from ultraviolet radiation in marine environments. In skincare, mycosporine glycine functions as both an antioxidant and a skin protectant.
The ingredient works by neutralising free radicals and helping to shield skin from UV-induced damage. Research suggests it may also play a role in reducing inflammation and supporting skin structure, though it is still relatively understudied compared to more established skincare actives.
Benefits for Your Skin
How It Works
Mycosporine glycine works primarily through antioxidant mechanisms. When skin is exposed to UV radiation, it generates reactive oxygen species (free radicals) that damage cells and break down structural proteins like collagen. Mycosporine glycine neutralises these free radicals, reducing oxidative stress and the inflammatory response that follows sun exposure.
Additionally, research indicates the ingredient may inhibit advanced glycation end-products (AGEs)—harmful protein crosslinks formed when sugar and protein interact. By slowing AGE formation, it may help preserve skin elasticity and reduce signs of photodamage over time.
Clinical Evidence & References
In-vivo studies on mice exposed to UVB radiation showed that mycosporine glycine treatment reduced erythema, wrinkling, collagen degradation, and mast cell infiltration compared to untreated controls. Treated skin also showed elevated levels of antioxidant enzymes, suggesting the ingredient enhances the skin's own protective systems.
Laboratory research demonstrates that mycosporine glycine inhibits glycation and collagenase activity more effectively than some established ingredients. However, human clinical data remains limited, and most evidence comes from cell and animal studies. Further research in human subjects would help establish optimal concentrations and real-world efficacy in cosmetic formulations.
Published Research
How to Use
Mycosporine glycine is most commonly encountered in sun protection and antioxidant serums. As it is a supporting antioxidant rather than a primary active, it works well in formulations alongside other protective ingredients like vitamin C, niacinamide, or established UV filters. Use consistently as part of your daily skincare routine, particularly on days when sun exposure is anticipated.
Safety & Precautions
Frequently Asked Questions
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