Antioxidant

Octanicotinoyl Epigallocatechin Gallate

INCI: OCTANICOTINOYL EPIGALLOCATECHIN GALLATE

Reviewed by Kate · Last updated 20 Jul 2026

Also known as: Octanicotinoyl Epigallocatechin Gallate

A stabilised green tea extract with antioxidant and soothing properties

Best For Skin Types

All, Sensitive, Mature

Addresses

Antioxidant protection, Redness, Fine lines, Environmental damage

Usage Frequency

Daily

What Is Octanicotinoyl Epigallocatechin Gallate?

Octanicotinoyl epigallocatechin gallate (EGCG) is a modified form of epigallocatechin gallate, the primary active catechin found in green tea leaves. This ingredient is created by chemically enhancing EGCG to improve its stability and performance in skincare formulations, addressing one of the challenges with using raw green tea extract in cosmetics.

In skincare, it functions primarily as an antioxidant, helping to neutralise free radicals and reduce oxidative stress on the skin. It also has anti-inflammatory properties that may help calm irritated skin and support the skin's natural repair processes.

Benefits for Your Skin

How It Works

EGCG works by scavenging free radicals—unstable molecules that damage skin cells and accelerate visible ageing. By neutralising these molecules before they can cause harm, the ingredient helps protect skin's structural proteins and support normal cellular function.

The anti-inflammatory mechanism appears to work through several pathways, including modulation of inflammatory signalling molecules in the skin. This may explain why green tea extracts have traditionally been used in skincare for calming and soothing purposes.

Clinical Evidence & References

Research on EGCG itself (the parent compound) suggests meaningful antioxidant and anti-inflammatory activity in laboratory and animal studies. Published work indicates potential benefits for managing signs of photoaging, including effects on skin elasticity, hydration and pigmentation, though most evidence comes from controlled laboratory settings rather than extensive human trials.

The modified form (octanicotinoyl EGCG) was developed to improve stability and skin penetration compared to standard EGCG, but human clinical data specific to this stabilised version appears limited. The ingredient shows promise based on its mechanism and preclinical work, but more research in human subjects would help clarify its real-world efficacy in skincare products.

How to Use

This ingredient is most effective when used consistently as part of a daily routine. It works well alongside other antioxidants and can be incorporated into serums, moisturisers or essences. As with any antioxidant ingredient, results develop over time with regular use rather than producing immediate visible changes.

Safety & Precautions

Green tea extracts and their derivatives are generally well-tolerated in skincare. As with any new ingredient, patch test first if you have particularly sensitive skin.

Frequently Asked Questions

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