Oligopeptide-107 Sh-Oligopeptide-1

Oligopeptide-107 Sh-Oligopeptide-1 is a synthetic peptide — a short chain of amino acids — that functions as a skin conditioning agent. It is sometimes referred to as a synthetic epidermal growth factor mimic, meaning it is designed to behave similarly to naturally occurring growth factors that help regulate skin cell behaviour and barrier health.In formulations, this ingredient is typically combined with hydrating and soothing agents such as hyaluronic acid, glycerol and botanical extracts. It works at the surface and upper layers of the skin to help maintain and restore barrier integrity.

This peptide is thought to work by mimicking signalling molecules that naturally occur in skin. These signals encourage cells in the epidermis (the outermost layer) to function optimally, supporting barrier repair and maintaining hydration levels.By promoting healthy barrier behaviour, the ingredient may help reduce water loss from the skin and limit the penetration of irritants, which in turn can reduce visible redness and inflammation. The exact mechanism is still being researched, but available evidence suggests it works best as part of a multi-ingredient formulation that includes other …

This ingredient is typically found in leave-on products such as moisturisers, serums and barrier-repair creams. Use as directed on the product packaging, usually twice daily. Since it is formulated alongside hydrating and soothing agents, consistency of use will likely yield better results than occasional application. It can generally be layered with other skincare steps without concern.

This peptide is generally well-tolerated with a low risk of irritation. Those with atopic dermatitis or sensitive skin may find it particularly suitable, though all new products should be patch-tested if you have a history of reactivity.