Anti-Sebum

Origanum Majorana Leaf Extract

INCI: ORIGANUM MAJORANA LEAF EXTRACT

Reviewed by Daisy · Last updated 14 Aug 2026

A plant extract with purifying and antioxidant properties traditionally used to support skin clarity

Best For Skin Types

Oily, Combination, Acne-prone

Addresses

Acne, Oil control, Redness

Usage Frequency

Daily

What Is Origanum Majorana Leaf Extract?

Origanum majorana leaf extract is derived from sweet marjoram, an herb in the mint family. The extract is typically prepared using ethanol, which concentrates bioactive compounds including rosmarinic acid, quercetin, apigenin and carvacrol—all of which possess antioxidant activity.

In skincare formulations, this ingredient functions as a tonic and refreshing agent. Its antimicrobial properties and ability to modulate inflammatory responses make it a candidate ingredient for formulations targeting oily or acne-prone skin, though it remains relatively uncommon in commercial products.

How It Works

The extract's primary mechanisms involve its polyphenolic compounds, which work through multiple pathways. The antioxidant compounds neutralise free radicals that contribute to oxidative stress and skin ageing. The antimicrobial components inhibit bacterial growth, whilst the anti-inflammatory constituents suppress inflammatory signalling pathways implicated in acne development.

Research using animal models has shown measurable reduction in skin inflammation markers, though translation to human skin efficacy at typical cosmetic concentrations requires further investigation.

Clinical Evidence & References

In vitro and animal studies demonstrate that ethanolic oregano extracts—which are botanically similar to marjoram—suppress inflammatory responses induced by acne-related bacteria, with one study showing approximately 32% reduction in induced skin inflammation in a mouse model. The extract also showed inhibitory effects on protein glycation, a process implicated in skin ageing.

However, these findings come from controlled laboratory and animal studies rather than human clinical trials. The typical concentration at which this ingredient appears in skincare products (around 0.1% of formulations) is considerably lower than those used in research, so direct translation to consumer benefits remains uncertain. Further human studies at cosmetic-relevant concentrations would strengthen the evidence base.

How to Use

This ingredient is most commonly encountered in toners, essences, or lightweight serums targeting oily or acne-prone skin. It can be used daily as part of a skincare routine. As with any botanical extract, introduce it gradually if you have sensitive skin, and use consistent sun protection since antioxidant ingredients work best alongside UV defence.

Safety & Precautions

Origanum majorana leaf extract is generally well-tolerated in cosmetic formulations. Those with sensitivity to plants in the Lamiaceae family (mint family) should exercise caution, as cross-reactivity is possible.

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Other forms of Origanum Majorana Leaf Extract

These appear on ingredients lists under different names but are the same substance. Origanum Majorana Leaf Extract is the common form.

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