Peptides

Palmitoyl Hexapeptide-12

INCI: palmitoyl oligopeptide

Reviewed by Kate · Last updated 18 Aug 2026

Skin-firming peptide with enhanced penetration

Addresses

ageing, loss of firmness, fine lines

What Is Palmitoyl Hexapeptide-12?

Palmitoyl Hexapeptide-12 is a six-amino-acid peptide modified with palmitic acid for improved skin penetration. This lipophilic modification allows the peptide to pass through the skin barrier more effectively to reach target cells.

The hexapeptide structure provides signalling benefits that support the skin's natural collagen and elastin production, contributing to improved firmness and reduced visible signs of ageing.

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