Polycaprolactone
INCI: POLYCAPROLACTONE
Reviewed by Kate · Last updated 14 Aug 2026
A stabilising polymer used in injectable skin treatments to support tissue structure
Best For Skin Types
All, Mature
Addresses
What Is Polycaprolactone?
Polycaprolactone is a synthetic polymer—a long-chain molecule made from repeating units of caprolactone. It belongs to a class of materials called polyesters and is used in skincare primarily as a stabilising agent in injectable formulations rather than as a topical ingredient.
In cosmetic applications, polycaprolactone functions to maintain the structural integrity and consistency of injectable products, helping them remain stable over time and deliver other active ingredients effectively to deeper skin layers.
How It Works
Polycaprolactone works by forming a stable matrix within injectable formulations. Its polymer structure allows it to encapsulate or support other active ingredients, preventing degradation and ensuring consistent delivery when injected into the skin.
The ingredient's biocompatibility means it can be used in products designed to stimulate the skin's natural regenerative response, though the mechanism depends partly on what other ingredients are present in the formulation.
Clinical Evidence & References
Research into polycaprolactone in dermatological use is limited but emerging. Animal studies suggest it may support skin wound healing and tissue regeneration when used in injectable formulations, particularly when combined with other ingredients such as hyaluronic acid.
However, the evidence base for polycaprolactone as a standalone skincare ingredient remains modest. Most research focuses on its use as a delivery vehicle in clinical injectable treatments rather than in over-the-counter skincare products. Further human studies would help clarify its long-term efficacy and safety profile in cosmetic applications.
Published Research
How to Use
Polycaprolactone is not typically found in traditional topical skincare products; it is primarily used in professional injectable treatments administered by qualified practitioners. If you are considering injectable skin rejuvenation treatments containing this ingredient, ensure they are performed by a trained dermatologist or aesthetic practitioner who can assess your individual needs and skin condition.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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