Retinyl Palmitate
INCI: Retinol
Reviewed by Daisy · Last updated 18 Aug 2026
Gentle Vitamin A ester for sensitive skin types
At a glance
Things to be aware of
Addresses
EWG Safety Score
What Is Retinyl Palmitate?
Retinyl Palmitate is a stable ester formed by combining retinol with palmitic acid. As one of the mildest members of the retinoid family, it requires conversion in the skin through several steps before becoming active retinoic acid, resulting in a gentler, more gradual effect.
While less potent than retinol or tretinoin, this derivative offers excellent stability in formulations and is well-tolerated by most skin types. It serves as an ideal entry point for those beginning their retinoid journey or those who cannot tolerate stronger forms.
Benefits for Your Skin
Clinical Evidence & References
- Antioxidants, November 2020
- International Journal of Toxicology, October 2017
- Journal of Biomedical Nanotechnology, February 2016, pages 394-403
- Acta Biochimica Polonica, 2015, pages 201-206
- Journal of Lipid Research, July 2013, pages 1,731–1,743
- Clinical Interventions in ageing, December 2006, pages 327-348
- Journal of Investigative Dermatology, November 2003, pages 1163-1167
Published Research
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Retinyl palmitate in skin: safety and biological effects Photodermatology, 2010
How widely it's used
Regulatory information
Standardised cosmetic-ingredient identifiers used by regulators.
Show identifiers
- INCI Name
- RETINYL PALMITATE
- EC Number
- 201-228-5
- Function
- Skin Conditioning
Frequently Asked Questions
From the Clinic
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