S-Pentadiplandra Brazzeana Defensin-Like Protein
INCI: S-PENTADIPLANDRA BRAZZEANA DEFENSIN-LIKE PROTEIN
Reviewed by Emma · Last updated 6 May 2026
A plant-derived protein with potential barrier-supporting properties
Best For Skin Types
All, Sensitive
Addresses
Usage Frequency
Daily
What Is S-Pentadiplandra Brazzeana Defensin-Like Protein?
S-Pentadiplandra Brazzeana Defensin-Like Protein is derived from the Pentadiplandra brazzeana plant and belongs to a class of naturally occurring proteins known as defensins. These proteins are found in plants as part of their natural defence mechanisms.
In skincare formulations, this ingredient is included for its theoretical role in supporting skin barrier function, though its cosmetic applications remain relatively understudied compared to more established actives.
How It Works
Defensin-like proteins are thought to work by interacting with the skin's outermost layers to support structural integrity and barrier function. The mechanism likely involves reinforcing the lipid and protein matrix that keeps moisture in and irritants out, though the specific pathways in human skin remain largely unexplored.
Clinical Evidence & References
Published research specifically examining this ingredient's efficacy in skincare is limited. Most evidence for defensin-like proteins comes from botanical and biochemical studies rather than human clinical trials on skin health. Without dedicated clinical studies, it is difficult to quantify its actual benefit to skin barrier function or other claimed properties.
If you are considering products containing this ingredient, they are best evaluated based on their overall formulation and any supporting data from the manufacturer, rather than on this single component alone.
How to Use
Use as directed by the product formulation. As this ingredient is typically found in serums, moisturisers, or barrier-repair products, apply to clean skin and allow time to absorb before layering other actives. Consistency over time is more likely to yield results than sporadic use.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizLearn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.