Silicone

Silicone Quaternium-22

INCI: SILICONE QUATERNIUM-22

Reviewed by Kate · Last updated 14 Aug 2026

Also known as: Silicone Quaternium-22

A silicone-based conditioning agent that smooths and protects hair

Best For Skin Types

All

Usage Frequency

Daily

What Is Silicone Quaternium-22?

Silicone Quaternium-22 is a positively charged silicone polymer, created by chemically modifying silicone molecules with a quaternary ammonium compound. This modification gives it conditioning properties and allows it to bind effectively to hair fibres. It is primarily used in haircare products rather than skincare.

The ingredient functions as a hair conditioning agent, depositing a protective film on the hair shaft to improve texture, reduce frizz, and enhance shine. Its use in skincare is minimal and typically appears in products designed to condition or protect hair that may come into contact with facial skin.

How It Works

Silicone Quaternium-22 adheres to hair through ionic attraction. The positive charge on the molecule binds to the negatively charged keratin protein in hair, creating a thin, continuous coating. This film smooths the cuticle layer of the hair shaft, reducing friction and improving light reflection.

The silicone layer also acts as a water-repellent barrier, reducing the amount of moisture that can penetrate the hair and cause swelling or frizz, particularly in humid environments.

Clinical Evidence & References

Silicone conditioning agents have a long history of use in haircare and are generally well-established as effective smoothing and conditioning ingredients. However, specific clinical data on Silicone Quaternium-22 itself is limited in published peer-reviewed literature.

The ingredient's mechanism of action — forming a protective film and improving hair surface properties — is consistent with how other silicone quaternium compounds perform, but individual efficacy data would strengthen the evidence base. Its safety profile appears sound based on decades of cosmetic use in similar products.

How to Use

This ingredient is primarily intended for haircare rather than direct facial skincare. If present in a product applied near the face or scalp, allow it to fully dry or rinse thoroughly to minimise migration onto facial skin. For those with sensitive skin or prone to congestion, apply to hair lengths and ends rather than roots or the scalp line.

Safety & Precautions

Silicone Quaternium-22 is generally well-tolerated and has a long safety history in cosmetics. It is unlikely to cause irritation, though those sensitive to silicones may wish to patch test products containing it.

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