Silicone

Silicone Quaternium-5

INCI: SILICONE QUATERNIUM-5

Reviewed by Emma · Last updated 2 Jun 2026

Also known as: Silicone Quaternium-5

A silicone-based conditioning agent that smooths hair and reduces static

Best For Skin Types

All

Addresses

Roughness, Texture

Usage Frequency

Daily

What Is Silicone Quaternium-5?

Silicone Quaternium-5 is a silicone-derived polymer that has been modified with a positively charged quaternary ammonium group. This chemical structure allows it to bind to hair and skin surfaces, where it deposits a thin, lightweight conditioning layer.

In skincare formulations, it functions primarily as a conditioning and antistatic agent. Silicones have been used safely in pharmaceutical and cosmetic applications since the 1940s, and are now present in approximately 60% of skincare products globally, where they are valued for their ability to create a smooth, non-greasy sensory experience.

How It Works

Silicone Quaternium-5 works through its positively charged molecular structure, which is attracted to the negatively charged surfaces of skin and hair. It adheres to these surfaces and forms a thin, continuous film that smooths irregularities and reduces friction.

This conditioning layer remains largely on the surface rather than penetrating deeply, which is why it contributes to texture and feel without significantly altering skin function. The antistatic effect occurs because the silicone coating reduces the electrical charge differential between the skin and the environment.

Clinical Evidence & References

Silicones, including silicone quaternium compounds, have an established safety profile in topical formulations. Research supports their use in pharmaceutical and cosmetic products, where they are recognised as well-tolerated ingredients that provide consistent sensory benefits.

However, specific clinical evidence examining the skin benefits of Silicone Quaternium-5 in particular is limited. Most research on silicones focuses on their safety and sensory characteristics rather than therapeutic skin outcomes. Further targeted studies would help clarify any specific dermatological benefits beyond texture enhancement.

How to Use

Silicone Quaternium-5 is typically formulated into rinse-off products (such as conditioners) or leave-on formulations where its conditioning effect is desired. Since it deposits on the surface, occasional gentle cleansing helps prevent buildup. In skincare products, it is usually part of a formula rather than a standalone ingredient, so follow the product instructions for application frequency and amount.

Safety & Precautions

Silicone Quaternium-5 is generally well-tolerated and considered safe for topical use in cosmetic formulations. Those with known sensitivity to silicones or склонность к buildup may wish to patch test first.

Frequently Asked Questions

From the Clinic

Not sure what your skin actually needs?

Two minutes, a few questions, and we’ll point you at what matters — no guesswork.

Take the skin quiz

Learn More About Skincare Ingredients

Explore our comprehensive ingredient glossary to understand what's in your products.

Browse All Ingredients

Authorised Stockist

Official UK retailer

Tracked Delivery

Free UK shipping over £50

5 Star Rating

Trusted by thousands

Expert Advice

Free consultations