Peptides

Tripeptide-29

Reviewed by Emma · Last updated 18 Aug 2026

Collagen-mimetic peptide for structural support

Best For Skin Types

All

Addresses

ageing, loss of firmness, wrinkles

What Is Tripeptide-29?

Tripeptide-29 is a biomimetic peptide that mimics a sequence found in collagen itself. This collagen fragment signals the skin to maintain and produce collagen, supporting the structural integrity of the dermal matrix.

By providing signals similar to those released during natural collagen turnover, this peptide helps maintain youthful skin structure without the complexity of delivering actual collagen to the skin.

How It Works

Tripeptide-29 is a synthetic, highly purified peptide consisting of amino acids glycine and proline plus amino acid derivative hydroxyproline. Applied to skin, it’s been shown to strengthen skin’s supportive elements. This improves uneven texture and the look of fine lines and also helps reverse a dehydrated appearance. Tripeptide-29’s small size allows it to easily penetrate skin’s uppermost layers so it can reach its target areas sooner. Typical usage level is between 0.1–1%.

Clinical Evidence & References

References:

  • Amino Acids, January 2018, pages 29-38 View Study
  • Journal of Cosmetic Dermatology, December 2016, pages 514-519 View Study
  • Journal of the Society of Cosmetic Scientists of Korea, 2010, pages 65-69 View Study

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