Vitis Vinifera Skin Extract
INCI: VITIS VINIFERA SKIN EXTRACT
Reviewed by Daisy · Last updated 14 Aug 2026
Also known as: Vitis Vinifera Skin Extract
A plant-derived antioxidant from grape skins that helps defend skin against oxidative stress
Best For Skin Types
All, Mature, Sensitive
Addresses
Usage Frequency
Daily
What Is Vitis Vinifera Skin Extract?
Vitis vinifera skin extract is derived from the skins of grape fruits and contains naturally occurring compounds with antioxidant properties. These compounds work by neutralising free radicals—unstable molecules generated by UV exposure and environmental stressors that can damage skin cells and contribute to visible signs of aging.
The extract is used in skincare formulations at relatively low concentrations, typically around 0.1% or less. It functions as an ingredient designed to support the skin's natural defence systems against oxidative damage.
Benefits for Your Skin
How It Works
The extract contains polyphenolic compounds that act as antioxidants. These molecules are capable of donating electrons to free radicals, effectively neutralising them before they can cause cellular damage. This mechanism is particularly relevant when skin is exposed to UV radiation or other environmental stressors that generate reactive oxygen species (ROS).
Emerging research suggests the extract may also influence gene expression patterns in skin cells exposed to UV stress, potentially supporting cellular recovery pathways. However, this aspect requires further investigation in human studies.
Clinical Evidence & References
Laboratory studies on Vitis vinifera skin extract demonstrate antioxidant activity and the ability to support skin cell function under UV stress. Research indicates the extract can upregulate genes associated with cellular defence and longevity (such as SIRT1) in stressed skin cells.
Most evidence to date comes from in vitro and ex vivo studies rather than human clinical trials. Whilst these findings are promising, more robust human studies are needed to establish the practical efficacy and optimal concentration ranges for cosmetic use.
Published Research
How to Use
Vitis vinifera skin extract is typically found in serums, creams, and other leave-on formulations. As an antioxidant ingredient, it works best as part of a broader skincare routine that includes sun protection—the extract supports defence against oxidative damage but does not replace the need for broad-spectrum SPF.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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