Zanthoxylum Piperitum Fruit Extract
INCI: ZANTHOXYLUM PIPERITUM FRUIT EXTRACT
Reviewed by Kate · Last updated 14 Aug 2026
A plant extract studied for its potential to reduce facial wrinkles through muscle relaxation
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Zanthoxylum Piperitum Fruit Extract?
Zanthoxylum piperitum fruit extract is derived from the fruits of the Japanese pepper plant, a species native to East Asia. The extract contains various phytochemical compounds that have been investigated for topical skincare applications.
In cosmetic formulations, this ingredient functions primarily as a skin conditioning agent. It is found in a small proportion of skincare products, typically at concentrations below 1%.
How It Works
Research indicates that Zanthoxylum piperitum fruit extract may work by inhibiting muscle contractions in a manner conceptually similar to botulinum toxin, but through a non-invasive topical application. This is thought to occur through interference with acetylcholine signalling at the neuromuscular junction, reducing the repeated muscle movements that contribute to expression lines.
Clinical Evidence & References
A controlled study demonstrated that topical application of Zanthoxylum piperitum extract improved lateral canthal wrinkles (fine lines around the outer eye) in human subjects. The extract showed measurable effects on muscle contraction inhibition in laboratory models.
However, evidence remains limited to a small number of studies. Larger, longer-term clinical trials would be needed to establish efficacy across different populations and to determine optimal concentrations for consistent results in finished skincare products.
How to Use
As this ingredient is typically present at low concentrations in formulations, it is unlikely to be the primary active in a product. Use products containing Zanthoxylum piperitum extract as part of a broader skincare routine. Results, if any, develop gradually over consistent use rather than immediately.
Safety & Precautions
Frequently Asked Questions
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