Soothing Agents

Zinc Chloride

INCI: ZINC CHLORIDE

Reviewed by Emma · Last updated 14 Aug 2026

A mineral salt with established uses in oral care and skin-soothing formulations

Best For Skin Types

Oily, Combination

Addresses

Redness, Oil control, Sensitivity

Usage Frequency

As directed by product instructions

What Is Zinc Chloride?

Zinc chloride is an inorganic salt composed of zinc and chlorine. It exists as a white crystalline powder and is soluble in water, making it suitable for incorporation into aqueous skincare and oral care products. The ingredient has a long history of use in clinical and pharmaceutical applications.

In skincare, zinc chloride is primarily used for its soothing and astringent properties. It appears in a small proportion of skincare products (approximately 0.2%), most commonly in formulations designed to calm irritated skin or support oral hygiene.

How It Works

Zinc chloride functions as an astringent, meaning it causes mild contraction of skin tissue. This action can help reduce the appearance of pores and may provide a tightening sensation on the skin surface. The ingredient also possesses mild antimicrobial properties, which may contribute to its use in oral care formulations.

When applied topically in dilute solutions, zinc chloride interacts with the outermost layers of skin, producing these astringent effects without penetrating deeply into the dermis.

Clinical Evidence & References

Zinc chloride has a well-established history in clinical dermatology, particularly in surgical applications where precision tissue removal is required. However, evidence specific to its use as a cosmetic skincare ingredient remains limited.

Research on zinc supplementation more broadly suggests that zinc supports skin health and immune function, though this typically refers to oral intake rather than topical application. Direct clinical studies examining the efficacy of topically applied zinc chloride in cosmetic formulations would strengthen the evidence base for its skincare benefits.

How to Use

Zinc chloride is typically found in rinse-off formulations such as toners, astringent solutions, or oral care products rather than leave-on treatments. If using a product containing this ingredient, follow the manufacturer's instructions regarding frequency and duration. For oral care products, use as directed on the packaging. For skincare, patch testing is advisable if you have sensitive skin, particularly if the product is intended to be used frequently.

Safety & Precautions

Zinc chloride is generally well-tolerated in cosmetic concentrations. As with any astringent ingredient, overuse may cause dryness or irritation in sensitive individuals. Avoid contact with eyes.

Frequently Asked Questions

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