Prebiotic/Probiotic/Postbiotic

Bacillus/Soybean Ferment Extract

INCI: BACILLUS/SOYBEAN FERMENT EXTRACT

Reviewed by Emma · Last updated 20 Jul 2026

A fermented soybean extract with potential skin-conditioning and soothing properties

Best For Skin Types

All, Sensitive

Addresses

Sensitivity, Redness, Irritation

Usage Frequency

Daily

What Is Bacillus/Soybean Ferment Extract?

Bacillus/Soybean Ferment Extract is produced by fermenting soybeans using Bacillus bacteria (such as Bacillus subtilis). This fermentation process breaks down the soybean's complex compounds into smaller, bioavailable molecules that may offer skincare benefits. The extract functions primarily as a skin conditioner in cosmetic formulations.

Fermented plant extracts have been used in traditional Asian skincare for centuries, and modern research has begun investigating their mechanisms. This particular ingredient appears in roughly 0.1% of skincare products, making it relatively uncommon in Western formulations.

How It Works

The fermentation process transforms soybeans into bioactive compounds that appear to work through multiple pathways. Research suggests the extract may suppress certain immune responses — particularly mast cell activity and the production of inflammatory cytokines like IL-31, which is involved in itch sensation. This may explain its potential benefit in reactive or atopic skin conditions.

The exact mechanisms remain incompletely understood, particularly in topical application. Most existing research has focused on ingested or animal-model studies, so the precise effects when applied to skin require further investigation.

Clinical Evidence & References

Animal studies using fermented soybean extracts have shown promising results for atopic dermatitis-like conditions, with effects comparable to prednisolone in reducing skin thickness and inflammatory markers. These studies also observed reduced scratching behaviour and lowered levels of itch-associated cytokines.

However, human clinical data on topical application is limited. The research available has primarily examined ingested fermented soybeans or extracts tested in laboratory and animal settings. More human trials would be needed to confirm efficacy and optimal concentrations for skincare use. Current evidence is intriguing but should be considered preliminary.

How to Use

This ingredient is typically found in serums, essences, and moisturisers at low concentrations. It integrates well into both AM and PM routines and may be particularly useful for those with reactive or inflammatory skin concerns. As with any new product, introduce it gradually and monitor your skin's response.

Safety & Precautions

Generally well-tolerated in topical formulations. However, individuals with soybean allergies — particularly those who have experienced allergic reactions to fermented soybean products — should exercise caution or avoid this ingredient.

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