C10-40 Isoalkylamidopropylethyldimonium Ethosulfate
INCI: C10-40 ISOALKYLAMIDOPROPYLETHYLDIMONIUM ETHOSULFATE
Reviewed by Daisy · Last updated 2 Jun 2026
Also known as: C10-40 Isoalkylamidopropylethyldimonium Ethosulfate
A conditioning agent that helps reduce static and improve hair manageability in rinse-off formulas
Usage Frequency
Daily or as directed
What Is C10-40 Isoalkylamidopropylethyldimonium Ethosulfate?
C10-40 Isoalkylamidopropylethyldimonium Ethosulfate is a quaternary ammonium compound (quat) commonly used in hair and scalp care products. Despite its complex name, it functions as a conditioning agent designed to coat the hair fibre and reduce friction between strands.
This ingredient is classified as an antistatic agent, meaning it helps neutralise the electrical charge that builds up on hair and can cause frizz, tangles, and flyaways. It is typically found in rinse-off formulas rather than leave-on skincare.
How It Works
The ingredient works through electrostatic principles. Hair develops a negative charge when wet or dry, which causes strands to repel one another and create frizz. C10-40 Isoalkylamidopropylethyldimonium Ethosulfate carries a positive charge that neutralises this repulsion, allowing hair to lie flatter and feel smoother.
Additionally, the hydrophobic (water-repelling) portion of the molecule adheres to the hair cuticle, forming a conditioning film. This film reduces friction between strands, making hair easier to comb and style whilst improving perceived texture and shine.
Clinical Evidence & References
Published clinical data specific to this ingredient is limited. Most evidence for its efficacy comes from cosmetic chemistry literature and manufacturer testing rather than independent peer-reviewed studies.
Industry data suggests it performs adequately as a conditioning and antistatic agent in rinse-off formulations. Like other quats, it is generally recognised as safe in cosmetic use at approved concentrations, though some jurisdictions maintain restrictions on certain quaternary ammonium compounds.
How to Use
This ingredient is primarily found in shampoos and conditioners designed for frizz control and detangling. It is rinsed off immediately after application, so exposure time is brief. For best results, use as directed on the product label—typically applying conditioner to mid-lengths and ends of damp hair, leaving for a few moments, then rinsing thoroughly.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Butter
A plant-derived occlusive that helps seal moisture and support the skin barrier
Butyl Avocadate
An ester derived from avocado pears
Butyrospermum Parkii Butter Unsaponifiables
A plant-derived conditioning agent from shea butter with skin-soothing potential
C14-28 Alkyl Acid
A conditioning agent derived from long-chain fatty acids, primarily used in hair care formulations
C20-24 Olefin
A lightweight conditioning agent that helps smooth and soften the skin's surface
Caesalpinia Sappan Bark Extract
A plant extract traditionally used in Asian skincare for gentle skin conditioning
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.