Best For Skin Types
All, Dry, Sensitive
Addresses
Usage Frequency
Daily
What Is Cannabis Sativa Stem Extract?
Cannabis sativa stem extract is derived from the stems of the cannabis plant, processed into a water-based or alcohol-based extract. Unlike extracts from cannabis leaves or flowers, stem extracts are non-intoxicating and contain cannabinoids and other plant compounds in minimal concentrations, if at all. The extract functions primarily as a humectant and skin conditioner in cosmetic formulations.
In skincare, this ingredient is included for its potential to support skin hydration and maintain the skin's natural moisture balance, though its full profile of bioactive compounds varies depending on extraction method and plant variety.
How It Works
Cannabis sativa stem extract appears to work through multiple mechanisms. As a humectant, it draws water into the stratum corneum, supporting skin hydration. The extract also contains polyphenols and other compounds with potential antioxidant activity, which may help neutralise reactive oxygen species generated by UV exposure and environmental stressors.
Early laboratory studies suggest the extract may modulate inflammatory pathways and support skin barrier function, though these mechanisms have primarily been demonstrated in cell cultures rather than human skin studies.
Clinical Evidence & References
Research into cannabis sativa stem extract remains limited in human trials. In vitro studies using fermented stem extracts have shown potential in reducing markers of photoaging, such as MMP-1 expression in UV-exposed fibroblasts, and in supporting antioxidant defences. However, these laboratory findings do not directly translate to proven benefits in living skin.
Some research on related cannabis varieties suggests anti-inflammatory potential, but evidence specific to stem extracts in human skincare is sparse. More clinical data would be needed to confirm efficacy for particular skin concerns. The ingredient is generally recognised as safe in cosmetic use, though individual tolerability varies.
Published Research
How to Use
Cannabis sativa stem extract is typically used in serums, moisturisers and hydrating products as part of a formulated blend. There is no established optimal concentration range for cosmetic use. As with any new skincare ingredient, introduce it gradually and observe how your skin responds over 2–4 weeks. It can be layered with other hydrating or antioxidant ingredients.
Safety & Precautions
Frequently Asked Questions
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