Cetrimonium Bromide
INCI: CETRIMONIUM BROMIDE
Reviewed by Emma · Last updated 14 Aug 2026
Also known as: Cetrimonium Bromide
A preservative and purifying agent that helps maintain product stability and safety
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Cetrimonium Bromide?
Cetrimonium bromide (CTAB) is a quaternary ammonium compound—a type of positively charged molecule derived from ammonium salts. In skincare formulations, it functions primarily as a preservative and antimicrobial agent, helping to prevent microbial contamination and extend product shelf life.
It also has antistatic and emulsifying properties, making it useful in formulations where these functions are needed. Whilst commonly used in disinfectant products, it appears in a small proportion of skincare products at relatively low concentrations.
How It Works
Cetrimonium bromide works by disrupting the cell membranes of bacteria and fungi. Its positively charged molecular structure allows it to interact with and destabilise the negatively charged outer layers of microbial cells, inhibiting their growth and reproduction.
In formulations, it also reduces static electricity and can help stabilise mixtures of oils and water-based ingredients through its emulsifying properties, contributing to overall product performance.
Clinical Evidence & References
Cetrimonium bromide has a documented history of antimicrobial effectiveness in clinical and industrial settings. However, research into its specific dermal effects in skincare formulations remains limited.
Available evidence suggests that quaternary ammonium compounds like cetrimonium bromide may carry a risk of contact sensitivity or irritation, particularly at higher concentrations, over prolonged exposure, or on compromised skin barriers. The research base for this ingredient in cosmetic skincare specifically is smaller than for its use as a surface disinfectant, so individual tolerance can vary.
How to Use
Products containing this ingredient should be used as directed. If you have a known sensitivity to quaternary ammonium compounds or a history of contact dermatitis, introduce any new product slowly and monitor your skin's response. Discontinue use if irritation develops.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
C16-17 Alkyl Benzoate
A lightweight ester that conditions skin and improves product texture
Calcium Paraben
A paraben preservative that prevents microbial growth in skincare formulations
Cassytha Filiformis Powder
A plant-derived powder with antioxidant and preservative properties
Cetrimonium Chloride
A quaternary ammonium preservative that protects formulations from microbial spoilage
Cetrimonium Methosulfate
A quaternary ammonium compound with purifying and conditioning properties
Chamomilla Recutita Flower/Leaf Extract
A botanical extract with mild purifying and soothing properties
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.