Fragrance

Citral

INCI: CITRAL

Reviewed by Kate · Last updated 14 Aug 2026

A naturally derived fragrance compound with emerging evidence for skin renewal and photoprotection

Best For Skin Types

All

Addresses

Photoprotection, Cell renewal

Effective Concentrations

0.1–1%

Usage Frequency

Daily

What Is Citral?

Citral is a naturally occurring compound found in citrus fruits and plants, characterised by its distinctive lemon scent. In skincare, it functions primarily as a fragrance ingredient, though it also appears in some formulations for its potential biological activity on skin cells.

This monoterpene is commonly used in the cosmetic industry to impart pleasant aromas to products and to mask less desirable odours from other ingredients. Beyond fragrance, research suggests citral may interact with skin cell signalling pathways involved in renewal and protection.

How It Works

Citral appears to stimulate skin renewal by binding to TRPV3, a receptor involved in keratinocyte (skin cell) proliferation. This interaction may promote the natural cycle of cell division and differentiation that maintains healthy skin structure.

In terms of photoprotection, animal studies suggest citral may offer some defensive activity against UVB-induced cellular damage, though the mechanism in human skin requires further investigation.

Clinical Evidence & References

Research in hairless mice demonstrated that topical citral application at concentrations of 0.1–1% reduced the incidence of UVB-induced skin cancers over a 24-week exposure period. However, this represents preliminary evidence from animal models and does not directly confirm protective effects in human skin.

Structural studies have shown that citral binds to the TRPV3 receptor, a pathway associated with skin renewal in cellular models. Evidence for skin renewal benefits in humans remains limited and would benefit from controlled clinical studies.

How to Use

Citral is typically incorporated into skincare formulations at low concentrations as a fragrance component. If using products containing citral, introduce them gradually to assess tolerance. Bear in mind that fragrance ingredients, whilst generally well-tolerated, can accumulate in products and may interact with other actives.

Safety & Precautions

Citral is a known fragrance allergen and may trigger sensitivity or contact dermatitis in susceptible individuals. It may also exacerbate rosacea or heighten skin irritation, particularly in those with reactive or compromised skin barriers.

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