Coenzyme Q10
INCI: Ubiquinone
Reviewed by Kate · Last updated 18 Aug 2026
Also known as: Ubiquinone
Vitamin-like, fat-soluble substance naturally present in the body May help improve the appearance of signs of ageing
EWG Safety Score
What Is Coenzyme Q10?
Coenzyme Q10, also known as ubiquinone, is a vitamin-like, fat-soluble substance naturally present in the body. A handful of studies have shown that coenzyme Q10 (CoQ10) may help improve the appearance of signs of ageing. There is also research showing that environmental factors deplete the presence of CoQ10 in the skin. The latest research suggests that topical application of CoQ10 has antioxidant and skin-soothing effects. As such, it is one of many helpful antioxidants for skin, but it is not the only one or the “best.”
Clinical Evidence & References
- Biofactors, November 2015, pages 383-390
- Biofactors, September-October 2009, issue 5, pages 435-441
- Biofactors, 2008, issue 4, pages 237-243
- Journal of Cosmetic Dermatology, March 2006, issue 1, pages 30-38
- Biofactors, November 2005, issue 4, pages 179-185
- Journal of Investigative Dermatology, 2005, issue 4, pages 12-13
- Journal of Dermatological Science, August 2001, Supplement, pages 1-4
Published Research
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Coenzyme Q10 in skin aging and energy production Biofactors, 2006
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Topical ubiquinone for skin rejuvenation Biochim Biophys Acta, 2007
Frequently Asked Questions
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