Skin Conditioning

Corthellus Shiitake Extract

INCI: CORTHELLUS SHIITAKE EXTRACT

Reviewed by Kate · Last updated 2 Jun 2026

A mushroom extract with antioxidant properties and potential skin-protective benefits

Best For Skin Types

All

Addresses

Oxidative stress, Fine lines, Barrier repair

Usage Frequency

As directed on product label

What Is Corthellus Shiitake Extract?

Shiitake mushroom extract is derived from Lentinula edodes, a culinary mushroom rich in polysaccharides, phenolic compounds, and β-glucans. These bioactive components are what give the extract its potential value in skincare formulations.

In topical products, shiitake extract functions primarily as a skin protectant, working to support the skin's natural defences against environmental stressors.

How It Works

Shiitake extract exerts its effects through multiple pathways. The polysaccharides and phenolic compounds present act as antioxidants, reducing oxidative damage caused by environmental factors. The extract also shows activity against elastase and collagenase — enzymes responsible for breaking down structural proteins in skin — which may help maintain skin firmness and resilience.

The β-glucans further support skin health by reinforcing barrier function and enhancing the skin's protective capacity against external irritants.

Clinical Evidence & References

Research into shiitake extract's skincare applications is still emerging. Available studies demonstrate that the extract does possess antioxidant activity and can inhibit enzymes linked to skin ageing, particularly elastase and collagenase. However, most evidence comes from in-vitro studies rather than human clinical trials.

Some research has examined melanin-inhibiting properties in cell models, though results vary depending on extract preparation and concentration. Long-term efficacy and optimal usage concentrations in cosmetic formulations remain areas requiring further investigation. The ingredient appears generally well-tolerated in topical applications based on current research, though studies on human skin are limited.

How to Use

Shiitake extract is typically incorporated into creams, serums, and essences at concentrations determined by the formulation. There is no specific guidance on usage frequency, as this depends on the broader product formulation and your individual skin tolerance. Use as directed on the product label.

Safety & Precautions

Shiitake extract appears to be well-tolerated in topical skincare applications. However, individuals with known mushroom allergies or sensitivities should exercise caution, as shiitake can occasionally trigger allergic responses in sensitive populations.

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