Croton Lechleri Resin
INCI: CROTON LECHLERI RESIN
Reviewed by Emma · Last updated 20 Jul 2026
Also known as: Croton Lechleri Resin
A resin extract with antioxidant and soothing properties from South American trees
Best For Skin Types
All, Sensitive
Addresses
Usage Frequency
Daily
What Is Croton Lechleri Resin?
Croton Lechleri Resin, commonly known as sangre de drago (dragon's blood), is a bright red viscous resin harvested from Croton lechleri trees native to South America. It has been used traditionally in regional medicine for various skin conditions.
In skincare formulations, it functions as an antioxidant, helping to protect skin from oxidative stress. The resin contains bioactive compounds that appear to have both antioxidant and anti-inflammatory properties when applied topically.
Benefits for Your Skin
How It Works
The resin's bioactive compounds work through multiple mechanisms. It acts as an antioxidant by neutralising free radicals that can damage skin cells and accelerate ageing. Additionally, research suggests it may reduce the release of substance P, a neuropeptide involved in neurogenic inflammation—a type of inflammation triggered by nerve activity in the skin.
This dual action—antioxidant protection combined with inflammatory pathway modulation—may contribute to its traditional use in treating various skin concerns, though more research is needed to fully understand its mechanisms in human skin.
Clinical Evidence & References
Limited clinical evidence exists. One small interventional study examined a cream combining Croton Lechleri Resin with seed oil for stretch marks, using biophysical measurements and ultrasound to assess outcomes. Whilst the formulation showed positive effects on skin condition parameters, the non-randomised design and limited scope mean findings should be viewed cautiously.
In vitro research demonstrates that the resin significantly reduces substance P release in a dose-dependent manner in laboratory models of skin inflammation. However, translating these results to real-world efficacy in human skin requires further investigation. The evidence base is modest; more robust clinical trials would help establish its true benefits and optimal concentrations for skincare use.
How to Use
Croton Lechleri Resin is typically incorporated into serums, creams, or balms as part of a broader formulation rather than used as a standalone ingredient. Follow the application instructions on your product's label. As with any active ingredient, introduce it gradually into your routine if you have sensitive skin, and pair it with a good moisturiser and sunscreen during the day. Results may take several weeks of consistent use to become apparent.
Safety & Precautions
Frequently Asked Questions
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