Skin Conditioning

Croton Lechleri Resin Extract

INCI: CROTON LECHLERI RESIN EXTRACT

Reviewed by Rosie · Last updated 14 Aug 2026

A resin extract traditionally used to support skin condition and reduce inflammatory responses

Best For Skin Types

All

Addresses

Stretch marks, Elasticity, Redness, Inflammation

Usage Frequency

Daily

What Is Croton Lechleri Resin Extract?

Croton Lechleri Resin Extract is derived from the bright red resin of the Croton lechleri tree, native to South American rainforests. Traditionally known as sangre de drago (dragon's blood), this ingredient has been used in indigenous skincare practices for generations. In cosmetic formulations, it functions as a skin conditioning agent with documented antioxidant and anti-inflammatory properties.

The resin is rich in bioactive compounds that appear to interact with skin physiology, particularly in relation to inflammatory pathways and skin elasticity.

How It Works

Croton Lechleri Resin Extract appears to work by modulating neurogenic inflammation, a process where nerve signals trigger inflammatory responses in the skin. Research indicates it can reduce the release of substance P, a neuropeptide involved in inflammation and skin sensitivity, with studies showing dose-dependent reductions of around 32% in controlled models.

The ingredient's antioxidant properties may also help neutralise free radicals and support the skin's natural repair processes, which could contribute to improved skin condition over time, particularly in areas prone to stretch marks or compromised elasticity.

Clinical Evidence & References

A clinical trial examining a cosmetic product containing Croton Lechleri Resin Extract alongside plant seed oil demonstrated improvements in striae distensae (stretch marks) when assessed through biophysical measurements and ultrasonographic evaluation. Participants showed measurable changes in skin texture and appearance, suggesting the ingredient may have practical value in addressing skin affected by elasticity loss.

In vitro research supports its anti-inflammatory mechanism by showing it can significantly reduce substance P release in a model of cutaneous neurogenic inflammation. However, most evidence comes from small-scale or preliminary studies, and more extensive clinical research would strengthen our understanding of its efficacy and optimal use in skincare formulations.

How to Use

Croton Lechleri Resin Extract is typically incorporated into creams or serums as part of a broader skincare formula. For concerns like stretch marks or skin elasticity, consistent use over several weeks is likely necessary before noticeable changes become apparent. It works well alongside other skin-conditioning ingredients and can be used as part of morning and evening routines.

Safety & Precautions

Generally well-tolerated in cosmetic formulations. As with any botanical extract, those with known sensitivities to South American plant materials should patch test first. No significant adverse effects have been reported in available literature.

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