Croton Lechleri Resin Extract
INCI: CROTON LECHLERI RESIN EXTRACT
Reviewed by Rosie · Last updated 14 Aug 2026
A resin extract traditionally used to support skin condition and reduce inflammatory responses
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Croton Lechleri Resin Extract?
Croton Lechleri Resin Extract is derived from the bright red resin of the Croton lechleri tree, native to South American rainforests. Traditionally known as sangre de drago (dragon's blood), this ingredient has been used in indigenous skincare practices for generations. In cosmetic formulations, it functions as a skin conditioning agent with documented antioxidant and anti-inflammatory properties.
The resin is rich in bioactive compounds that appear to interact with skin physiology, particularly in relation to inflammatory pathways and skin elasticity.
How It Works
Croton Lechleri Resin Extract appears to work by modulating neurogenic inflammation, a process where nerve signals trigger inflammatory responses in the skin. Research indicates it can reduce the release of substance P, a neuropeptide involved in inflammation and skin sensitivity, with studies showing dose-dependent reductions of around 32% in controlled models.
The ingredient's antioxidant properties may also help neutralise free radicals and support the skin's natural repair processes, which could contribute to improved skin condition over time, particularly in areas prone to stretch marks or compromised elasticity.
Clinical Evidence & References
A clinical trial examining a cosmetic product containing Croton Lechleri Resin Extract alongside plant seed oil demonstrated improvements in striae distensae (stretch marks) when assessed through biophysical measurements and ultrasonographic evaluation. Participants showed measurable changes in skin texture and appearance, suggesting the ingredient may have practical value in addressing skin affected by elasticity loss.
In vitro research supports its anti-inflammatory mechanism by showing it can significantly reduce substance P release in a model of cutaneous neurogenic inflammation. However, most evidence comes from small-scale or preliminary studies, and more extensive clinical research would strengthen our understanding of its efficacy and optimal use in skincare formulations.
How to Use
Croton Lechleri Resin Extract is typically incorporated into creams or serums as part of a broader skincare formula. For concerns like stretch marks or skin elasticity, consistent use over several weeks is likely necessary before noticeable changes become apparent. It works well alongside other skin-conditioning ingredients and can be used as part of morning and evening routines.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Crithmum Maritimum Callus Culture Filtrate Extract
Plant cell extract derived from sea fennel, used to support skin's protective functions
Crocus Sativus Leaf Cell Culture Extract
A plant cell culture extract that supports the skin's natural protective mechanisms
Crocus Sativus Stigma Water
A floral water derived from saffron crocus stigmas, traditionally valued for skin conditioning
Croton Lechleri Sap Extract
Amazonian plant sap with traditional use and emerging evidence for skin conditioning
Cryptomeria Japonica Bud Extract
A plant extract with antioxidant and skin-conditioning properties from Japanese cypress buds
Crystallins
Structural proteins with potential skin-conditioning and protective properties
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.